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How is Crohn’s disease different from IBS?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 29-year-old female and have had stomach pain, diarrhoea, weight loss, and extreme fatigue for several months. My doctor thinks I might have Crohn’s disease, as they saw inflammation in my small intestine in imaging tests. Can you break it down for us, in layman’s terms, as to how Crohn’s disease is different from irritable bowel syndrome (IBS) or plain acidity issues? I am concerned about possible long-term complications, like nutrient deficiencies, and whether this could affect my chances of having a healthy pregnancy in the future.

  • Are biologic medications safe for women in their 20s to take if they have Crohn’s disease?
  • Is it a good idea to get a second opinion from a doctor who specialises in inflammatory bowel disease (IBD) before I begin treatment?

Kindly help.

Answered by Dr. Ashraf Ghani

Education:

MD

Professional Bio:

Dr. Ashraf Ghani is a dedicated general medicine physician committed to providing comprehensive and evidence-based healthcare for adult patients. He has experience in diagnosing and managing a wide range of acute and chronic medical conditions, including diabetes, hypertension, infections, respiratory illnesses, and lifestyle-related disorders. Dr. Ashraf Ghani focuses on accurate diagnosis, preventive care, and personalized treatment plans tailored to each patient's needs. Known for his compassionate and patient-centered approach, Dr. Ashraf Ghani strives to help patients achieve better health through clear communication and quality medical care.  

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I hear your concern, and it’s completely understandable. Living with chronic stomach pain, diarrhoea and fatigue is exhausting, and the uncertainty as to the cause can bring a lot of anxiety.

Crohn's disease is an inflammatory condition that develops when the immune system attacks parts of the digestive tract, leading to swelling, ulcers and gradual damage.

Crohn’s can damage the intestinal lining and may result in complications such as strictures, fistulas, or poor nutrient absorption, unlike irritable bowel syndrome (IBS), which involves changes in bowel habits and discomfort without visible inflammation or tissue injury, or simple acidity and indigestion.

This could account for the weight loss and tiredness, as the body may not be absorbing sufficient vitamins, iron or protein. Crohn’s can cause anaemia, vitamin deficiencies and sometimes surgery if not properly controlled, but many people live full, active lives with today's treatment options.

Biologics are drugs that target specific parts of the immune system. They are generally safe for young adults and are often used safely before and during pregnancy.

Crohn’s can be complex and requires medication management, monitoring, and nutritional support. A second opinion from an IBD specialist before starting biologics can help provide peace of mind and allow for your treatment to be personalised to your specific needs.

You are asking questions and planning for your long-term health and fertility, which is the right step. Early and specific treatment can help control inflammation, prevent complications, and help you regain your strength and sense of well-being.

I hope this addresses your concerns.

Thanks and regards.

Medically reviewed by iCliniq medical review team
Published At June 2, 2026
Reviewed At July 8, 2026

Education:

MD

Professional Bio:

Dr. Ashraf Ghani is a dedicated general medicine physician committed to providing comprehensive and evidence-based healthcare for adult patients. He has experience in diagnosing and managing a wide range of acute and chronic medical conditions, including diabetes, hypertension, infections, respiratory illnesses, and lifestyle-related disorders. Dr. Ashraf Ghani focuses on accurate diagnosis, preventive care, and personalized treatment plans tailored to each patient's needs. Known for his compassionate and patient-centered approach, Dr. Ashraf Ghani strives to help patients achieve better health through clear communication and quality medical care.  

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Ashraf Ghani is a dedicated general medicine physician committed to providing comprehensive and evidence-based healthcare for adult patients. He has experience in diagnosing and managing a wide range of acute and chronic medical conditions, including diabetes, hypertension, infections, respiratory illnesses, and lifestyle-related disorders. Dr. Ashraf Ghani focuses on accurate diagnosis, preventive care, and personalized treatment plans tailored to each patient's needs. Known for his compassionate and patient-centered approach, Dr. Ashraf Ghani strives to help patients achieve better health through clear communication and quality medical care.  

This doctor is not available for online consultations on the platform anymore.

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