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Will taking Sibelium for migraine delay the periods?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been taking Sibelium 10 mg for the last few weeks for my migraine, and last month I missed my period.

Kindly clarify the reason. Is it delaying due to this medicine?

Please help.
Answered by Dr. Ohams Ike Henry

Education:

MBBS

Professional Bio:

Dr. Ohams Ike Henry is an experienced General Practitioner with expertise in primary healthcare, chronic disease management, acute care, and preventive medicine. He is skilled in diagnosing and treating a wide range of medical conditions across all age groups. Dr. Henry is dedicated to delivering patient-centered care, promoting healthy lifestyles, and ensuring long-term wellness through evidence-based clinical practices and compassionate support.

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Hello,

Welcome to icliniq.com.

On the aspect of missing your period, the migraine prescription medication, Sibelium (Flunarizine), has some effect of blocking the dopamine receptor in the brain.

Besides, it has a calcium channel blocking effect. So the possibility is that blocking the dopamine receptor will cause a central increase in prolactin. Prolactin will lead to galactorrhea and, in turn, alter the menstrual cycle.

So it is a possibility, if you have done a pregnancy test and it is negative. So that dopaminergic antagonists may cause amenorrhea.

I hope this helps.

Thank you.

Medically reviewed by Dr. Nithila. A
Published At June 9, 2019
Reviewed At October 16, 2025

Education:

MBBS

Professional Bio:

Dr. Ohams Ike Henry is an experienced General Practitioner with expertise in primary healthcare, chronic disease management, acute care, and preventive medicine. He is skilled in diagnosing and treating a wide range of medical conditions across all age groups. Dr. Henry is dedicated to delivering patient-centered care, promoting healthy lifestyles, and ensuring long-term wellness through evidence-based clinical practices and compassionate support.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. Nithila A is a Dental Surgeon specializing in providing comprehensive oral healthcare. She focuses on preventive care, routine dental treatments, and patient education to maintain optimal oral health. Known for her compassionate and patient-centered approach, she ensures comfortable and effective dental care tailored to the individual needs of each patient.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ohams Ike Henry
Dr. Ohams Ike Henry

General Practitioner

Education:

MBBS

Professional Bio:

Dr. Ohams Ike Henry is an experienced General Practitioner with expertise in primary healthcare, chronic disease management, acute care, and preventive medicine. He is skilled in diagnosing and treating a wide range of medical conditions across all age groups. Dr. Henry is dedicated to delivering patient-centered care, promoting healthy lifestyles, and ensuring long-term wellness through evidence-based clinical practices and compassionate support.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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