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Will taking Sibelium for migraine delay the periods?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been taking Sibelium 10 mg for the last few weeks for my migraine, and last month I missed my period.

Kindly clarify the reason. Is it delaying due to this medicine?

Please help.

Hello,

Welcome to icliniq.com.

On the aspect of missing your period, the migraine prescription medication, Sibelium (Flunarizine), has some effect of blocking the dopamine receptor in the brain.

Besides, it has a calcium channel blocking effect. So the possibility is that blocking the dopamine receptor will cause a central increase in prolactin. Prolactin will lead to galactorrhea and, in turn, alter the menstrual cycle.

So it is a possibility, if you have done a pregnancy test and it is negative. So that dopaminergic antagonists may cause amenorrhea.

I hope this helps.

Thank you.

Medically reviewed byDr. Nithila. A

Published At June 9, 2019
Reviewed AtOctober 16, 2025

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