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How to treat persistent feelings of sadness and low energy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been experiencing persistent feelings of sadness and low energy for several months. I lack motivation and no longer find joy in activities that used to make me happy. While I continue to meet my responsibilities at work and with my family, I often feel emotionally numb or overwhelmed.

I am sleeping more than usual, yet I still feel constantly tired. At times, I even question whether it is worth continuing to feel this way. A few weeks ago, I started taking an antidepressant, but I have not noticed much improvement yet. Please tell me the following:

  1. How long does it typically take for these medications to start working?
  2. Should I also consider starting therapy?

I truly want to feel like myself again.

Please help.

Thank you.

Answered by Dr. Georges Hany Kozah

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

Antidepressants such as SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotonin-norepinephrine reuptake inhibitors) typically take about two to six weeks to begin easing symptoms, and up to eight to twelve weeks to reach their full effect. Early improvements may include better sleep, a bit more energy, or less anxiety, while improvements in mood and motivation often come later. Since you have only been on your medication for a few weeks, you may be right at the point where changes start to show.

However, if you notice no improvement at all after six weeks or if symptoms worsen, your doctor may consider adjusting the dose or switching medications. Therapy is also highly recommended, especially cognitive behavioral therapy (CBT), which works well alongside medication. It can help you work through the emotional numbness, lack of motivation, and overwhelming thoughts you have described.

The feeling of wondering whether it is worth continuing like this is a serious sign of depression and not something to ignore. You are not alone, and help is available. If these thoughts persist, please speak to a mental health professional as soon as possible. In the meantime, continue taking your medication as prescribed, reach out for therapy, and try to maintain a basic routine that includes sunlight, regular meals, and light activity. If at any point you feel at risk of hurting yourself, contact a crisis line, seek urgent care, or speak with someone you trust. Your well-being matters, and support is out there for you.

I hope you are satisfied with my answer.

For further queries, you can consult me at iCliniq.

Thank you.

Medically reviewed by iCliniq medical review team
Published At August 1, 2025
Reviewed At June 24, 2026

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MD

Professional Bio:

Dr. Georges Hany Kozah is an experienced Lebanese Gynecologist with an MD from The Lebanese University Faculty of Medical Sciences (2016) and a Fellowship completed in 2022. Specializing in high-risk obstetrics, advanced ultrasound, oncology, colposcopy, and hysteroscopy, he combines expertise with a patient-centered approach. Passionate about women’s health, Dr. Kozah strives for excellence and optimal outcomes in collaborative, innovative care.

This doctor is not available for online consultations on the platform anymore.

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