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Can HIV be prevented after three days of unprotected sex?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi,

I had sexual (vaginal only) intercourse three days back with a woman whom I had known for a few days. She looked like a normal regular kind of girl. So I had sex without protection. But after the sex, I doubt she has other sex partners also, and she often has sex. So now I am feeling unsafe. And somewhere, I read that within 72 hours of unprotected sex, there are some medical precautions to prevent HIV?

Please suggest something.

Thank you.

Hello,

Welcome to icliniq.com.

I read your query and understand your concern. Post-exposure prophylaxis (PEP) is a combination of three drugs. You can take them once or twice a day for the next 28 days. For adults, the suggested dosage is Tenofovir Disoproxil 300 mg and Emtricitabine 200 mg (these two drugs come in one pill) once daily. A third drug, either Raltegravir 400 mg twice daily or Dolutegravir 50 mg daily.

I hope I have answered your question.

Let me know if I can assist you further.

Thank you.

Medically reviewed byDr. K. Shobana

Published At June 14, 2022
Reviewed AtJune 26, 2025

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