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Why did I test positive for IgE RAST?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My test report was negative in the IgE test a year ago. Now I got a positive IgE RAST for gluten, eggs, peanut butter, and milk.

What might be the cause?

I have struggled with sinus issues all my life, and currently, I am taking Singular when needed and Benadryl. I was referred to an ENT specialist or allergist because of recurring sinus infections.

Kindly help.

Thank you.

Answered by Dr. Shyam Kalyan N

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

Specific immunoglobulin E (IgE) testing for allergens is not as accurate as skin prick allergy testing. It is possible to have a negative result in one and a positive in another. The factors affecting the result could be the test itself or the reagents and the lab.

I suggest skin prick allergy testing. This is the gold standard for allergy diagnosis. The allergens you have tested positive for are all foods that are slightly less important in your condition as they are more likely to be caused by inhalant aeroallergens.

  1. Have you checked sensitivities for aeroallergens for your allergy or sinus symptoms?
  2. Did they check sensitivities to dust mites, cockroaches, insects, funguses, pollens, and animal dander?

Please reply for further management.

Thank you.

Patient's Query

Hello doctor,

Thank you for your reply.

They are not just the new immunoglobulin E (IgE) for food allergies. I eat all these foods, and I have never reacted negatively, but based on this test, I am so scared to eat any of them because my doctor said it can potentially cause anaphylaxis.

  1. It limits what I am eating. How do I find out if I am allergic for sure?
  2. And should I cut all these foods as my doctor said?

Please help.

Thank you.

Answered by Dr. Shyam Kalyan N

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

Although you had all these foods till now and they did not cause any harm, it is not very sound that suddenly you turned allergic to these, and consuming them now would result in life-threatening anaphylaxis.

Till we get a final diagnosis, avoid consuming these. Get tested for these substances again using the skin prick method and not via specific IgE. I suggest a skin prick allergy test for these food allergens as well as the aeroallergens.

I hope this helps.

Thank you.

Medically reviewed by Dr. Sneha Kannan
Published At March 19, 2022
Reviewed At October 24, 2025

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Sneha Kannan is a skilled Dental Surgeon with expertise in providing general dental care, including scaling, fillings, and preventive treatments. She does oral surgery procedures such as extractions and minor surgical interventions. She does procedures in restorative dentistry, including crowns, bridges, and dentures. She is an expert in doing endodontic treatments such as root canal therapy. She is well-versed in doing procedures in cosmetic dentistry, including teeth whitening and smile correction. She can provide pediatric dental care for children’s oral health and preventive treatments. She promotes oral hygiene awareness and preventive dental practices.  

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Shyam Kalyan N is a highly skilled Allergy and ENT Specialist dedicated to diagnosing and treating a wide range of ear, nose, throat, and allergy-related conditions. With expertise in advanced ENT care and allergy management, he provides personalized treatment plans that improve overall health and quality of life. Known for his patient-focused approach and clinical excellence, he combines modern medical practices with compassionate care to ensure long-term wellness.

This doctor is not available for online consultations on the platform anymore.

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