Q. My platelet count is high and it differs each month. Should I consult a hematologist?

Answered by
Dr. Mubashir Razzaq Khan
and medically reviewed by Dr. Vinodhini. J
This is a premium question & answer published on Dec 20, 2020 and last reviewed on: Jan 21, 2021

Hi doctor,

I am a 27-year-old female. I have dyslipidemia and currently taking Lipanthyl. I have been taking blood tests and consult my doctor every month for five months. I manage to reduce my cholesterol, but the doctor is concerned with my platelet count right now. I have attached my blood platelet count for the past five months.

The first month- 506.

The second month - 476.

The third month - 475.

The fourth month - 475.

Current reading - 525.

The doctor has referred me to consult the hematologist. Should I really go consult the hematologist, or is this a normal blood platelet count?



Welcome to icliniq.com.

In the case of elevated platelets, grade 1 thrombocytosis: platelets range between 550-649.

In grade 2, thrombocytosis: platelets range between 650-749.

Grade 3 thrombocytosis: 750-849.

Grade 4 thrombocytosis: 850-1099.

Grade 5 thrombocytosis: 1100 or more.

Elevated platelets are seen in iron deficiency anemia, infections, inflammation, drug-induced, and very rarely, it could be a part of essential thrombocythemia. Rule out the causes of secondary thrombocytosis. If all causes are excluded, get JAK2, Exon12, and CALR mutations tested. Even in primary thrombocytosis, also called essential thrombocythemia, these mutations are negative frequently.

In cases of secondary thrombocytosis, the treatment of elevated platelets is to treat the cause. In primary thrombocythemia, if JAK2 is negative, the treatment is cytoreductive therapy by hydroxyurea. The goal is to keep platelets below 1000. Thrombolytic drugs such as Aspirin, Clopidogrel, and Warfarin are also a part of therapy.

For JAK2 positive patients, Ruxolitinib tablets are given in a dose of 5 to 15 mg per day. Another option is IFN alpha in low dose (45 ug/week) in both JAK2 positive or negative cases. CALR positive cases show superior results in this mode. It could take years to cure the disease. This is not a life-threatening disease unless thromboembolism involves the heart, lungs, or/and brain. Sometimes, the first manifestation of the disease is thromboembolic events.

Was this answer helpful?


Related Questions:
Is it normal to have high platelet count in a high blood pressure patient?

I have high blood pressure problem from the last one month (silent BP) and my kidneys are damaging beacuse of this and my platelet count is 12 lakhs ...   Read full

What are the reasons for high platelet count?

My platelet count is high at 9 lakhs in routine CBC ... The platelet count is above the normal range ...   Read full

Can you see the attached CBC report, and let me know if there is anything serious ?

If hemoglobinopathy is suspected, then HPLC (high-performance liquid chromatography) can be done ...   Read full

Also Read Answers From:

Comprehensive Medical Second Opinion.Submit your Case

Related Questions & Answers

My platelet is high with 4 gm hemoglobin. What is my problem?

Query: Hello doctor, My platelet count was 974, hemoglobin was 4, sedimentation rate was >140, and iron was 7 with a saturation of 1%. I went to the doctor because I lost vision in one eye for about an hour. They have done and MRI, and EKG both normal. Two units of blood and iron transfusions started...  Read Full »

Can infection on penis cause severe itching?

Query: Hi doctor, I am suffering from an infection on my penis. I am using Clotrimazole cream over the infection. Once I miss applying cream a day, the penis gets infected with red patches, pus-filled boils and there is severe itching. My partner is not affected by any problem though we are sexually activ...  Read Full »

Ringworm Infections

Article Overview: This article discusses in detail the preventive measures for ringworm infections. Read Article

Dr. Vinay Kumar

Medical Name: Tinea corporis This is an infective condition of the skin that is caused by fungus which has tendency to grow fast in the hot, humid regions of the body. Facts About Ringworm Infections: Ring worm infection affects people of all age groups and has a worldwide distribution. It...  Read Article

Also Read

Sinusitis - Causes, Symptoms and Treatment
Sinusitis is the infection of the air cavities within the nasal passages. Normally, the healthy sinuses are filled with ...  Read more»
Asthma and Its Rising Incidence
This article explains about asthma and its causes. It also focuses on the benefits of starting early treatment to lead a...  Read more»
Parkinson's Disease: Historical Aspects and Current Treatment Approaches
This article discusses the historical aspects of Parkinsonism and, the evidence based approaches currently available for...  Read more»

Ask your health query to a doctor online?

Ask a Hematologist Now

* guaranteed answer within 4 hours.

Disclaimer: All health Q&As published on this website are not intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek the advice from your physician or other qualified health-care providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.