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Q. What is the importance of bioavailable testosterone?

Answered by
Dr. Bindiya Thakkar
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Aug 27, 2016 and last reviewed on: Jul 17, 2020

Hi doctor,

My husband was found to have elevated testosterone (over 1009 - the limit of the test), but normal LH and other hormones. A testicular ultrasound was normal. What are the possible diagnoses? Could Graves' disease cause this?

Dr. Bindiya Thakkar

Diabetology Endocrinology
#

Hi,

Welcome to icliniq.com.

  • Graves' disease does not cause high testosterone.
  • I have a few questions. What medicine he is taking now? What is his age?
  • Is he on any supplements? What was the bioavailable testosterone?

Revert back with the answers to the above questions to an endocrinologist online --> https://www.icliniq.com/ask-a-doctor-online/endocrinologist


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Thank you doctor,

He is 30 years old. He is not on any medication or supplement. We have not got the free testosterone results yet.

Dr. Bindiya Thakkar

Diabetology Endocrinology
#

Hi,

Welcome back to icliniq.com.

  • The first and foremost thing is to rule out exogenous exposure. If that is not the case, then wait for bioavailable levels.
  • If high, then I would recommend doing another set, but at 8 AM along with TSH (thyroid-stimulating hormone), cortisol, ACTH (adrenocorticotropic hormone), LH (Luteinizing hormone) and FSH (follicle stimulating hormone).
  • Is there any high blood pressure or diabetes or cholesterol or fractures? Did you observe any change in his behavior like aggression? Also, who is doing the evaluating him?

Revert back with the answers to the above questions to an endocrinologist online --> https://www.icliniq.com/ask-a-doctor-online/endocrinologist


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Hi doctor,

An endocrinologist at this point. Do you suggest any potential diagnosis other than an adrenal tumor? What will the bioavailable tell us? No high blood pressure, diabetes, fractures, high cholesterol or behavior changes. Also, definitely no exogenous sources.

Dr. Bindiya Thakkar

Diabetology Endocrinology
#

Hi,

Welcome back to icliniq.com.

  • Bioavailable testosterone will tell you true or active testosterone levels. Total level can be falsely high as its measurement depends on the protein in the body.
  • I would consider pituitary too, as a source.

For further information consult an endocrinologist online --> https://www.icliniq.com/ask-a-doctor-online/endocrinologist


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