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What is the reason for high monocyte and eosinophil?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My blood reports show high monocytes and eosinophils for over two years of span. I feel there is no energy, muscle spasms, splenomegaly, muscle pain, and malaise. I am seropositive RA. But, my CRP and ESR are normal most of the time.

Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

Rheumatoid arthritis is one of the causes for high monocyte count and multisystemic involvement.

Hence, treatment for that is nonsteroidal anti-inflammatory drugs and disease modifying drugs like Leflunomide, etc.

The high eosinophil count causes include allergy, parasitic infection, skin conditions and pulmonary eosinophilia, etc. According to the cause, the specific treatment can be given.

For allergy, antiallergic medication like Fexofenadine is useful.

You have not mentioned total count value, peripheral smear examination and value of differential count. So peripheral smear examination and clinical correlation needed in such case.

Please consult your physician for examination and get further work up according to the need. Take care.

Medically reviewed by Dr. K. Shobana
Published At June 5, 2018
Reviewed At July 31, 2025

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

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