Hla B27 Antigen

HLA-B27 blood test helps to identify HLA-B27 antigen in the body. HLA B27 antigen stands for human leukocyte antigen B27. It is a protein present on the surface of white blood cells. This protein helps the body's immune system identify differences between healthy tissues and foreign substances causing infection.

Recently Answered Questions Recently Answered Questions

All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

I have ankle and calf muscle pain. Could it be RA?

Query: Hello doctor, I am a 38-year-old male, suffering from RA from the last two years and recently started the treatment with an orthopedic doctor for AVN of the hip. I have been told by my orthopedician at icliniq to consult a rheumatologist for my ankle and calf muscle pain, and for my RA medication an...  Read Full »


Dr. Srivastava Durgesh

Answer: Hello, Welcome to icliniq.com. After going through the details of your query, there are a few things to be clarified first. You have not mentioned any involvement of the small joints of hands, wrists or feet. The joints you have mentioned only include large joints. If it is really so, then the l...  Read Full »

Can HLA B27 positve male with ankylosing spondylitis affect his children?

Query: Hello doctor, I am 26 years, and I had a hip resurfacing surgery eight years back. I am an HLA B27 positive, even my father is also positive. I have had joint pain for the last fourteen years. Now, I wish to know that if I marry and have children will this pass on to them? What measures should I ta...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. About 80 % of people with ankylosing spondylitis have HLA B27 positive, and only 1 to 4 % of people with positive HLA B27 develop ankylosing spondylitis. That means out of 100 people with positive HLA B27, only one to four can develop ankylosing spondylitis, and 96 t...  Read Full »

Is surgery needed for a labrum tear?

Query: Hello doctor, My wife has been diagnosed with a labrum tear. She is 37 years old. She wants to get a second opinion on the treatment options. Is surgery the only option available? Will not the labrum heal on its own? Currently, she is on ayurvedic treatment. I have attached a few files for your refe...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I went through the copies of the investigations you posted (attachment removed to protect patient identity). My interpretations are as follows: 1. She has arthritis of the hip joint with features of sacroiliitis (inflammation of one or both of the sacroiliac joints) as...  Read Full »

Why did the pain on the right side of my back move to the hips?

Query: Hi doctor, I have pain in my hips. I began to have a slight ache on the right side of the lower back and then it got moved to my hip-deep in the socket like a toothache. I have pain in my bones also for the past two days. Taking a hot water bath helped me and I was able to move around a little bi...  Read Full »


Dr. Rajiv Ranjan Kumar

Answer: Hi, Welcome to icliniq.com. Based on your history, the common rheumatological condition that needs to be ruled out is spondyloarthritis (SPA). It includes many groups of diseases starting from ankylosing spondylitis, reactive arthritis, and others. It causes back pain, lower limb arthritis and it ...  Read Full »

How dangerous is staphylococcus infection?

Query: Hi doctor, I had unprotected sex two months back and developed Streptococcal infection within a day. I took Amoxicillin to get rid of it. Within five days developed yeast infection and got treatment for that. Now, I have reactive arthritis. I got two painless red bumps on the back of my hand and I d...  Read Full »


Dr. Naval Mendiratta

Answer: Hi, Welcome to icliniq.com Could you give me the exact duration of the disease? Which are the joints involved in your case? For reactive arthritis (painful form of inflammatory arthritis), you do not need much of treatment. It normally subsides by itself. NSAIDs (nonsteroidal anti-inflammator...  Read Full »

I have been suffering from joint pains for the last two years. Kindly help.

Query: Hi doctor,I have been suffering from joint pain for the last two years. I get pain in fingers, palms, knee joints, heels, and soles. I consulted many doctors, and they suggested tablets Colchicine, Dolo, Myotop, and Nucoxia whenever I get pain. But these days, I am getting the pain very frequently, ...  Read Full »


Dr. Lokesh

Answer: Hi,Welcome to icliniq.com.It seems to be related to inflammatory arthritis. Your laboratory reports are not clear (attachment removed to protect the patient's identity). Please attach them again.   Read Full »

Does an increase in uric acid and creatinine levels indicate a damaged kidney?

Query: Hi doctor, I am a 42 year old male. From the past three months, I was suffering from typhoid. Now, I have pain in knees, sole, back, and wrist joints. The test reports show high sensitivity c-reactive protein (hs-CRP) 7.67, eGFR 68, folate 2, uric acid 7.7, creatinine 1.02, total cholesterol 211, tr...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. You mentioned that you had typhoid three months back, and now have features of large joint arthritis. With this profile, it seems to be reactive arthritis. If you have heel pain, which is more in the morning once you get up from the bed and put your feet on the ground,...  Read Full »

Why am I having constant left lower back pain after an injury?

Query: Hello doctor, I have had a lower back injury for three years, and that has not been improved with rehabilitation or anything. There is a constant pain in the left side of my lower back, which becomes worse on twisting motions, exercise and bending to the point where I can barely walk. My physiother...  Read Full »


Dr. Sumit Chawla

Answer: Hello, Welcome to icliniq.com. Your iliolumbar ligament is completely visualized and is free from any pathology in the MRI (attachment removed to protect patient identity). Your vertebra, intervertebral disc, spinal column, and spinal cord are also grossly normal. However, there is early facet arthr...  Read Full »

Does my scan report suggest the cause of my low back pain?

Query: Hi doctor, I do not remember any spine trauma. I do have morning stiffness of greater than one hour with will become better with movement. I have this issue for the past seven years. My HLA-B27 is positive. Am I suffering from inflammatory spondyloarthropathy or ankylosing spondylitis? I have attac...  Read Full »


Dr. Vivek Chail

Answer: Hi, Welcome to icliniq.com. The SI joints show minimal linear hyperintensity on STIR (short TI inversion recovery) sequence (attachment removed to protect patient identity). It is mild edema and not the usual findings which are seen in inflammatory spondyloarthropathy. Probably, it is in the early s...  Read Full »

My friend has sacroiliitis. Will it affect her family life and pregnancy?

Query: Hi doctor,A friend of mine, who is a 28 year old female, had been diagnosed with sacroiliitis before five years. She had been on painkillers (Indocap) for three years, which she was taking on a daily basis. Then for a year, her doctor advised her to have maintenance doses of Remicade infusions and s...  Read Full »


Dr. Divya Agarwal

Answer: Hi,Welcome to icliniq.com.This problem is called spondyloarthritis, and it is associated with a gene called HLA-B27.It is a chronic disease where there may be periods of relapses and remission.There maybe flare up of disease during pregnancy or post pregnancy. Otherwise, it generally does not cause ...  Read Full »

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