Hla B27 Antigen

HLA-B27 blood test helps to identify HLA-B27 antigen in the body. HLA B27 antigen stands for human leukocyte antigen B27. It is a protein present on the surface of white blood cells. This protein helps the body's immune system identify differences between healthy tissues and foreign substances causing infection.

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Why did the pain on the right side of my back move to the hips?

Query: Hi doctor, I have pain in my hips. I began to have a slight ache on the right side of the lower back and then it got moved to my hip-deep in the socket like a toothache. I have pain in my bones also for the past two days. Taking a hot water bath helped me and I was able to move around a little bi...  Read Full »


Dr. Rajiv Ranjan Kumar

Answer: Hi, Welcome to icliniq.com. Based on your history, the common rheumatological condition that needs to be ruled out is spondyloarthritis (SPA). It includes many groups of diseases starting from ankylosing spondylitis, reactive arthritis, and others. It causes back pain, lower limb arthritis and it ...  Read Full »

How dangerous is staphylococcus infection?

Query: Hi doctor, I had unprotected sex two months back and developed Streptococcal infection within a day. I took Amoxicillin to get rid of it. Within five days developed yeast infection and got treatment for that. Now, I have reactive arthritis. I got two painless red bumps on the back of my hand and I d...  Read Full »


Dr. Naval Mendiratta

Answer: Hi, Welcome to icliniq.com Could you give me the exact duration of the disease? Which are the joints involved in your case? For reactive arthritis (painful form of inflammatory arthritis), you do not need much of treatment. It normally subsides by itself. NSAIDs (nonsteroidal anti-inflammator...  Read Full »

I have been suffering from joint pains for the last two years. Kindly help.

Query: Hi doctor,I have been suffering from joint pain for the last two years. I get pain in fingers, palms, knee joints, heels, and soles. I consulted many doctors, and they suggested tablets Colchicine, Dolo, Myotop, and Nucoxia whenever I get pain. But these days, I am getting the pain very frequently, ...  Read Full »


Dr. Lokesh

Answer: Hi,Welcome to icliniq.com.It seems to be related to inflammatory arthritis. Your laboratory reports are not clear (attachment removed to protect the patient's identity). Please attach them again.   Read Full »

Does an increase in uric acid and creatinine levels indicate a damaged kidney?

Query: Hi doctor, I am a 42 year old male. From the past three months, I was suffering from typhoid. Now, I have pain in knees, sole, back, and wrist joints. The test reports show high sensitivity c-reactive protein (hs-CRP) 7.67, eGFR 68, folate 2, uric acid 7.7, creatinine 1.02, total cholesterol 211, tr...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. You mentioned that you had typhoid three months back, and now have features of large joint arthritis. With this profile, it seems to be reactive arthritis. If you have heel pain, which is more in the morning once you get up from the bed and put your feet on the ground,...  Read Full »

Why am I having constant left lower back pain after an injury?

Query: Hello doctor, I have had a lower back injury for three years, and that has not been improved with rehabilitation or anything. There is a constant pain in the left side of my lower back, which becomes worse on twisting motions, exercise and bending to the point where I can barely walk. My physiother...  Read Full »


Dr. Sumit Chawla

Answer: Hello, Welcome to icliniq.com. Your iliolumbar ligament is completely visualized and is free from any pathology in the MRI (attachment removed to protect patient identity). Your vertebra, intervertebral disc, spinal column, and spinal cord are also grossly normal. However, there is early facet arthr...  Read Full »

Does my scan report suggest the cause of my low back pain?

Query: Hi doctor, I do not remember any spine trauma. I do have morning stiffness of greater than one hour with will become better with movement. I have this issue for the past seven years. My HLA-B27 is positive. Am I suffering from inflammatory spondyloarthropathy or ankylosing spondylitis? I have attac...  Read Full »


Dr. Vivek Chail

Answer: Hi, Welcome to icliniq.com. The SI joints show minimal linear hyperintensity on STIR (short TI inversion recovery) sequence (attachment removed to protect patient identity). It is mild edema and not the usual findings which are seen in inflammatory spondyloarthropathy. Probably, it is in the early s...  Read Full »

My friend has sacroiliitis. Will it affect her family life and pregnancy?

Query: Hi doctor,A friend of mine, who is a 28 year old female, had been diagnosed with sacroiliitis before five years. She had been on painkillers (Indocap) for three years, which she was taking on a daily basis. Then for a year, her doctor advised her to have maintenance doses of Remicade infusions and s...  Read Full »


Dr. Divya Agarwal

Answer: Hi,Welcome to icliniq.com.This problem is called spondyloarthritis, and it is associated with a gene called HLA-B27.It is a chronic disease where there may be periods of relapses and remission.There maybe flare up of disease during pregnancy or post pregnancy. Otherwise, it generally does not cause ...  Read Full »

Can I donate blood with spondyloarthritis?

Query: Hello doctor, I am an 18-year-old female. Six months ago, I did some blood tests and my doctor said that I resulted in positive HLA-B27 and that she suspects me to have spondyloarthritis. But she did not explain to me things that I can or cannot do from now on. I take one tablet of vitamin D weekly...  Read Full »


Dr. Rajiv Ranjan Kumar

Answer: Hi, Welcome to icliniq.com. Spondyloarthritis (SpA) is a group of disorders which predominantly affects (inflammation or arthritis) in the spine and lower limbs. The common diseases which comes under SpA are ankylosing spondylitis, reactive arthritis, psoriatic arthritis, etc. HLA- B27 is a gene ...  Read Full »

Will Ankylosing spondylitis cause pain in lower ribs?

Query: Hello doctor, I have been having pain around my lower ribs towards the back side (left side) since the past eight days. The pain gets worse while lying down and trying to change sides in the night. It also hurts while sneezing or coughing (feels better if I cough or sneeze by holding the area with ...  Read Full »


Dr. Divya Agarwal

Answer: Hi, Welcome to icliniq.com. In the light of the fact that you are HLA B27 positive, the pain that you are experiencing is due to the same problem. This is called enthesitis, and it occurs due to inflammation at the attachment of muscles to bones. So the treatment also remains similar to that of AS...  Read Full »

Are vitreous cells found in anterior uveitis?

Query: Hi doctor, I was diagnosed with bilateral anterior uveitis two months back. I was put on Pred Forte. After 20 days of which only occasional AC cells were seen in right eye with no flare. Left eye was clear, but few mid vitreous cells were seen which were not present before. Hence, I was still on Pre...  Read Full »


Dr. Vaibhev Mittal

Answer: Hi, Welcome to icliniq.com. I think you have anterior uveitis in both eyes. Few vitreous cells can be present in anterior uveitis patient also. Usually, anterior uveitis is in one eye, but if bilateral we investigate them as it was done in your case. So, now you are HLA B27 positive (human leukocy...  Read Full »

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