HLA-B27 blood test helps to identify HLA-B27 antigen in the body. HLA B27 antigen stands for human leukocyte antigen B27. It is a protein present on the surface of white blood cells. This protein helps the body's immune system identify differences between healthy tissues and foreign substances causing infection.
All the answers published in this website are written by verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.
Does Adalimumab injection causes kidney dysfunction in HLA-B27 positive patients?
Query: Hello doctor, I am a 26-year-old male. I am HLA-B27 positive (hereditary issue). I am suffering from joint pains since the last 16 years, I generally use Ultracet to suppress the pain. I have undergone a resurfacing surgery before nine years. Since then I have not taken any treatment. I have visit... Read Full »
Answer: Hello, Welcome to icliniq.com. You need to understand that every medicine has its side effects and it is not that everyone gets it. Important is treatment. Since your disease may get worse with the passing years, Adalimumab injections would help you in controlling your disease. It rarely affects the... Read Full »
Is it safe to take Gabapentin for back stiffness?
Query: Hello doctor, I am a 33 year old unmarried male, and I have a back stiffness problem for more than three years. Everyone gives the says that my posture is not proper while walking. Two years back when I consulted a doctor, he suspected ankylosing spondylitis, but HLA-B27 was negative. After seeing... Read Full »
Answer: Hello, Welcome to icliniq.com. I have seen the attached reports (attachment removed to protect patient identity). The diagnosis of ankylosing spondylitis is a clinical and radiological diagnosis. The clinical criteria is a history of inflammatory back pain, and the pain is worse in mornings and ... Read Full »
I have ankle and calf muscle pain. Could it be RA?
Query: Hello doctor, I am a 38-year-old male, suffering from RA from the last two years and recently started the treatment with an orthopedic doctor for AVN of the hip. I have been told by my orthopedician at icliniq to consult a rheumatologist for my ankle and calf muscle pain, and for my RA medication an... Read Full »
Answer: Hello, Welcome to icliniq.com. After going through the details of your query, there are a few things to be clarified first. You have not mentioned any involvement of the small joints of hands, wrists or feet. The joints you have mentioned only include large joints. If it is really so, then the li... Read Full »
Why did the pain on the right side of my back move to the hips?
Query: Hi doctor, I have pain in my hips. I began to have a slight ache on the right side of the lower back and then it got moved to my hip-deep in the socket like a toothache. I have pain in my bones also for the past two days. Taking a hot water bath helped me and I was able to move around a little bi... Read Full »
Answer: Hi, Welcome to icliniq.com. Based on your history, the common rheumatological condition that needs to be ruled out is spondyloarthritis (SPA). It includes many groups of diseases starting from ankylosing spondylitis, reactive arthritis, and others. It causes back pain, lower limb arthritis and it ... Read Full »
My friend has sacroiliitis. Will it affect her family life and pregnancy?
Query: Hi doctor,A friend of mine, who is a 28 year old female, had been diagnosed with sacroiliitis before five years. She had been on painkillers (Indocap) for three years, which she was taking on a daily basis. Then for a year, her doctor advised her to have maintenance doses of Remicade infusions and s... Read Full »
Answer: Hi, Welcome to icliniq.com. This problem is called spondyloarthritis, and it is associated with a gene called HLA-B27. It is a chronic disease where there may be periods of relapses and remission. There maybe flare up of disease during pregnancy or post pregnancy. Otherwise, it generally does n... Read Full »
Is surgery needed for a labrum tear?
Query: Hello doctor, My wife has been diagnosed with a labrum tear. She is 37 years old. She wants to get a second opinion on the treatment options. Is surgery the only option available? Will not the labrum heal on its own? Currently, she is on ayurvedic treatment. I have attached a few files for your refe... Read Full »
Answer: Hello, Welcome to icliniq.com. I went through the copies of the investigations you posted (attachment removed to protect patient identity). My interpretations are as follows: 1. She has arthritis of the hip joint with features of sacroiliitis (inflammation of one or both of the sacroiliac joints)... Read Full »
I am a 25-year-old female and my HLA-B27 is positive. What could be the reason?
Query: Hi doctor, I am a 25-year-old female. For the last two months, I have had some pains in the right ear (back side) and neck. I went for some tests, and I came to know that HLA-B27 is positive. I am currently working and cannot concentrate as I get severe pain. I have a few questions regarding HLA-B2... Read Full »
Answer: Hi, Welcome to icliniq.com. I understand your concern. Please answer the following questions to know further details. Did you have any redness in your eye, also? (the reason for eye drops). Do you have pain in the back, also? Is your neck pain worst in the morning time? HLA (human leukocyte antigens... Read Full »
Can HLA B27 positve male with ankylosing spondylitis affect his children?
Query: Hello doctor, I am 26 years, and I had a hip resurfacing surgery eight years back. I am an HLA B27 positive, even my father is also positive. I have had joint pain for the last fourteen years. Now, I wish to know that if I marry and have children will this pass on to them? What measures should I ta... Read Full »
Answer: Hello, Welcome to icliniq.com. About 80 % of people with ankylosing spondylitis have HLA B27 positive, and only 1 to 4 % of people with positive HLA B27 develop ankylosing spondylitis. That means out of 100 people with positive HLA B27, only one to four can develop ankylosing spondylitis, and 96 t... Read Full »
How dangerous is staphylococcus infection?
Query: Hi doctor, I had unprotected sex two months back and developed Streptococcal infection within a day. I took Amoxicillin to get rid of it. Within five days developed yeast infection and got treatment for that. Now, I have reactive arthritis. I got two painless red bumps on the back of my hand and I d... Read Full »
Answer: Hi, Welcome to icliniq.com Could you give me the exact duration of the disease? Which are the joints involved in your case? For reactive arthritis (painful form of inflammatory arthritis), you do not need much of treatment. It normally subsides by itself. NSAIDs (nonsteroidal anti-inflammator... Read Full »
I have been suffering from joint pains for the last two years. Kindly help.
Query: Hi doctor,I have been suffering from joint pain for the last two years. I get pain in fingers, palms, knee joints, heels, and soles. I consulted many doctors, and they suggested tablets Colchicine, Dolo, Myotop, and Nucoxia whenever I get pain. But these days, I am getting the pain very frequently, ... Read Full »
Answer: Hi,Welcome to icliniq.com.It seems to be related to inflammatory arthritis. Your laboratory reports are not clear (attachment removed to protect the patient's identity). Please attach them again. Read Full »