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What are the differential diagnosis of hyperthyroidism?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I saw a patient who is a 33-year-old female with hyperthyroidism, have undergone partial thyroidectomy 10 years ago and complained of bilateral lower extremities numbness. Upon examination, it was found that the patient is pale and weak. I would be grateful if I could get five differential diagnoses and the main diagnosis since this is for my project purpose.

Thank you.

Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and understand your concern.

You have mentioned pallor on physical examination. Hence investigation with CBC (complete blood count) and peripheral smear examination has to be done. If the Hemoglobin level is low and macroovalocytes are seen then vitamin B12 deficiency has to be ruled out by serum B12 estimation. Second other causes for peripheral neuropathy has to be ruled out if B12 deficiency is not present. These other causes include diabetic neuropathy, calcium deficiency, potassium-like electrolyte deficiency, and hypothyroidism also have to be ruled out by serum TSH, and T4 estimation. History regarding liver disease, kidney disease, and alcohol has to be ruled out. If on physical examination radiculopathy like nerve compression is suspected then CT (computed tomography) spine investigation might be needed. According to the cause. further specific treatment can be given. If vitamin deficiency is found then treat with vitamin tablets or injections. Consult your specialist doctor, discuss with him or her, and take the medicines with their consent. As far as primary diagnosis is concerned without physical examination it is difficult to reach one cause, but as pallor is present vitamin B12 deficiency seems most likely here.

Take care.Hope your concern is solved.

Regards.

Medically reviewed by iCliniq medical review team
Published At August 14, 2023
Reviewed At May 8, 2026

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

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