Iron Over Absorption

Iron over absorption or hemochromatosis is a condition where a person absorbs a lot of iron from the food they consume. If left untreated, symptoms like abdominal pain, skin turning bronze, tiredness, weakness, weight loss, cirrhosis of the liver, and pancreatitis occurs.

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Do I have ferroportin disease if my ferritin level and transferrin saturation are high?

Query: Hello doctor, I am a 29-year-old male, and I fear that I might have ferroportin disease. I persistently have high ferritin levels, and my transferrin saturation is also mildly above the normal range. I have also looked at my genotyping on chromosome 2 and noticed a single nucleotide mutation for m...  Read Full »

Dr. Ajeet Kumar Lohana

Answer: Hello, Welcome to Having H63D (histidine at amino acid position 63) carrier does not indicate a diagnosis of hemochromatosis. Similarly, you have one of the gene alleles for ferroportin disease. However, the transferrin saturation should be low in ferroportin disease. On the...  Read Full »

What causes an iron deficiency or over absorption?

Query: Hi doctor, My TIBC 508, transferrin 363, transferrin saturation 17%, iron 85 and total LDH 109. Do these values indicate iron deficiency or over absorption? I am on regular Synthyroid, Singulair, Prilosec, Vitamin C and oral contraceptive. Thank you.  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to Based on your query and attached reports (attachment removed to protect patient identity), my opinion is as follows: It appears to be an early iron deficiency. Serum ferritin would have been more helpful in gauging the iron stores. Interaction between vitamin C and oral ...  Read Full »

How can excess iron be removed from heart and liver in a thalessemia patient?

Query: Hello doctor, My brother is a Thalassemia major patient. He goes through regular bi-weekly blood transfusions. He has been also taking one Desferal injection on daily basis. Recently T2 MRI scan was done for him which shows a severe amount of iron in heart and liver. I need your expert advice on ch...  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to Sorry to hear about your brother condition. To treat chronic iron overload in the body due to thalassemia major, he can be given an intravenous injection or subcutaneous infusion of Desferal. Usually, in such case, 1 to 2 gm daily dose of Desferal might be needed. Th...  Read Full »

I am passing black stools since two days. Why?

Query: Hi doctor, I am passing black stools since two days. I am on medication since four months. The current medication I am taking is Irozorb and Cranbe. Please suggest me what to do.  Read Full »

Dr. Sadaf Mustafa

Answer: Hello. Welcome to Iron in Irozorb can make the stools black or it may be happening due to gastritis or stomach ulcers. It is the iron that oxidizes and give black color, but it seems like you are taking these medications since four months. Did you have black color stools before? ...  Read Full »

How to reduce my serum ferritin level?

Query: Hi doctor, My ferritin level is 1500, and I want to bring it down to 150. How much will one DFO IV session or each Exjade pill reduce the ferritin level on an average? I am a healthy individual, and I do not have HIV, HCC, or any other disease.  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to Your serum ferritin is high, so the cause should be found out first. It can be hemochromatosis, in which excess iron is stored in the bone marrow. Deferoxamine is used for increased iron storage in thalassemia patient. For high ferritin, phlebotomy is also another mode o...  Read Full »

My kid has dark stools when she drinks soy milk. Why?

Query: Hello doctor, My kid is 19 months old and she has asthma. We are giving her 200 ml of fortified soy milk twice a day as she is not interested in drinking regular milk. She has dark stools when she drinks soy milk. Is it safe to give soy milk to kids?  Read Full »

Dr. Faisal Abdul Karim Malim

Answer: Hello, Welcome to Yes, it is safe to give soy milk to the child as long as she is not known to have any soy-protein allergy. Please check for the iron content of the soy-milk product that you are giving. It most probably must be because of the iron-content of the soy-milk product that t...  Read Full »

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