My ferritin level is 1500, and I want to bring it down to 150. How much will one DFO IV session or each Exjade pill reduce the ferritin level on an average? I am a healthy individual, and I do not have HIV, HCC, or any other disease.Related Questions:
• Can you please provide a diet chart for a thalassemia patient?
• Is thalassemia minor genetic?
• What diet will you recommend for a beta major thalassemia patient?
Thank you for replying. I am already aware of these things. I usually use phlebotomy, but it takes a while to get it to 150. We have checked for other diseases in the past, but there does not appear to be any disease. I simply absorb more iron, and I think I eat iron-rich foods. I want to understand more about the subject before approaching a specialist, so my questions can be more informed. So to put it perhaps another way. If you were treating a newly diagnosed person with thalassemia or another disease, where there is too much iron in the body, and you want to remove it, how much would each pill of Deferoxamine or each IV treatment of DFO decrease serum ferritin on average? I am looking for some specific numbers. Obviously, an average, with a range, as I expect it would vary from person to person a bit. But roughly, what kind of orders of magnitude would the ferritin drop after the IV or after each daily pill? I am trying to get an idea of how effective it is per dosage, so I can compare it to giving blood, which I am familiar with. So, I am looking for a specific, numerical answer, if you do not mind. Thank you.
Thank you doctor,
That is helpful. So, 3 mg per day with subcutaneous versus 200 mg for a blood donation. It does sound like the blood donations are far more effective. How does 200 mg translate into ferritin levels? If I lose 200 mg of ferric iron, how much roughly does the ferritin drop? As you gave me the statistics for DFO subcutaneously, how much are the comparative figures of iron chelation for each pill of Exjade and Deferiprone? How many grams of ferric iron would that bind? If you can give me these figures, I will be able to make an informed decision. We do intend to test genomic factors too. Thanks.
Related Questions & Answers
I have a swollen lymph node in the armpit. Does it indicate any health issue?
Hello doctor,I have swollen lymph node in the armpit with very little pain. I have been experiencing fatigue and weight loss for last few weeks. I have gone through some routine lab test and found that some test results are out of the normal range. Iron profile: iron 153, UIBC 96 (low), TIBC 249,... Read Full »
Dr. Sagar Ramesh Makode
Welcome to icliniq.com.
Serum iron is a bit on the high normal side and TIBC/ UIBC is on the lower side. The rest of the reports are fine. ESR is normal, so it makes the possibility of chronic inflammatory illness to be less likely.
However, your iron profile is not complete, serum ferriti...
Read Full »
Hemochromatosis and Iron Overload: Causes, Diagnosis, Clinical Presentation and Management
Hemochromatosis is a congenital condition in which an HFE gene mutation is present. So, increased iron absorption occurs irrespective of intake. More iron gets accumulated and iron storage increases. If the condition progresses, then iron gets accumulated in other organs apart from bone marrow like in liver, spleen, myocardium, joints, testes, skin, etc. Lets read more about this condition. Read Article »
Dr. Parth R Goswami
Hemochromatosis is a congenital condition in which an HFE gene mutation is present. So, increased iron absorption occurs irrespective of intake. More iron gets accumulated, and iron storage increases. If the condition progresses, then iron gets accumulated in other organs apart from bone marrow like ...
Read Article »
In thalassemia minor, is HbA1c test a reliable one?
I am diabetic since last 9 years and thalassemia minor as well. Recently, the fatigue symptoms have increased, especially when I am not able to sleep properly. I am 45 years old. My height is 167.5 cm and weight is 85 kg. Being thalassemia minor, is my HbA1c test reliable to decide my dia... Read Full »
Dr. Geeta Priyadarsini Kamminana
Internal Medicine Physician
Welcome to icliniq.com.
The main ailment you are presently worried with is fatigue and sleeplessness or insomnia.
Sleep affects our ability to think, react, remember and solve problems. I would like to know your sleep history.
How long you have had sleep problem? For how many days at a stret...
Read Full »