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What could cause iron deficiency or iron over-absorption?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My TIBC is 508, transferrin is 363, transferrin saturation is 17%, iron is 85, and total LDH is 109. Do these values indicate iron deficiency or overabsorption?

I am on regular Synthyroid, Singulair, Prilosec, vitamin C, and oral contraceptives.

Please advise.

Thank you.

Hi,

Welcome to icliniq.com.

I understand your concern.

Based on your query and attached reports (attachment removed to protect patient identity), my opinion is as follows:

It appears to be an early iron deficiency. Serum ferritin would have been more helpful in gauging the iron stores. The interaction between vitamin C and oral contraceptives has caused an abnormality in the values of LDH (lactate dehydrogenase). The variations are really mild to be thought of as anything abnormal.

Overabsorption of iron never occurs unless there is a hereditary condition like hemosiderosis (iron overload disorder) or other chronic conditions. At present, there is nothing to worry. Continue the same medications, as this mild variation is not to be worried about.

After six months, repeat the serum ferritin. It is one of the better indicators of deficiency or excess storage. At present, only a mild variation due to interactions between various medications. Continue with an iron and protein-rich diet. Also, you do not need any additional supplements for these.

I hope this helps you.

Thank you.

Medically reviewed byiCliniq medical review team

Published At October 19, 2016
Reviewed AtMay 19, 2026

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