I underwent cryotherapy for a lump, but the biopsy report suggests it is a leiomyoma. What is the chance of developing a lump after cryotherapy?

Q. Can someone develop a lump after four sessions of cryotherapy?

Answered by
Dr. Dhepe Snehal Madhav
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Apr 09, 2023 and last reviewed on: Sep 22, 2023

Hi doctor,

I had cryotherapy of about four sessions for a lump on my scrotum. It had not completely been eradicated, so the doctor sent it for a biopsy. The doctor thought it may have been a genital wart. The biopsy then came back, saying it was a leiomyoma cell that had spindle cells positive for desmin and SMA.

I would like to know that after cryotherapy could anyone develop a wart or is there any chance that it is just a scar from the cryotherapy or are these two things are different?

Thank you.



Welcome to icliniq.com.

Leiomyoma is a benign tumor arising from spindle cells that are confirmed on the biopsy and the additional report added to it at the end whereas a wart is an infective lesion (viral infection). It is a benign leiomyoma as per the attached reports (attachment removed for patient identity protection), not a wart. Skin biopsy of the wart will show mature squamous cells with a large clear perinuclear zone with a smudgy nucleus.

Thank you.

Hi doctor,

Thank you for your answer.

Please tell me if a scar would show differently.

Thank you.



Welcome back to icliniq.com.

Immunohistochemical markers are done to differentiate the leiomyoma and scar as both can appear the same on histopathological biopsy. This means that IHC (Immunohistochemical) has been a confirmatory additional test that has helped in your diagnosis (benign leiomyoma) as per the report (attachment removed for patient identity protection) you have sent.

Accordingly, to IHC reports it is a benign Leiomyoma.

Attach clinical picture to assess lesion clinically.

Thank you.

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