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Kindly advice on monoclonal B cell lymphocytosis.

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Patient's Query

Hello doctor,

I am 46 years old. I have been diagnosed with monoclonal B cell lymphocytosis. B-cell markers CD19 is 36 %, CD 20 is 33 %, and CD 22 is 3%. Dual expression Cd19/Cd5 is 31 %, Cd19/Cd23 is 31%, Cd19/Cd10 1 %. Blood was lymphoid gated. B-cell population co-expresses CD 45, 5, 19, 23, 20 dim and without surface light chain expression, and these comprise 31 % of lymphocytes 1.9 times.

Kindly advice.
Answered by Dr. Prakash. H. M.

Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

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Hello,

Welcome to icliniq.com.

Based on your query, my opinion is as follows,

1. Going through the markers and the count, a diagnosis of MBL (monoclonal B-cell lymphocytosis) can be thought of.

2. Absolute counts are only mildly increased. Need to watch for rising counts and any lymph nodes in the future.

3. Usually, the population, if checked as a whole, more than 7 % show MBL. However, progression to CLL is low. Only follow-up with blood counts and clinical examination for lymph nodes is necessary. No further tests are necessary for now. I hope it helps. Any further queries, here to help again.

Investigations to be done

Repeat counts after six months.
Medically reviewed by Dr. Nithila. A
Published At July 18, 2019
Reviewed At May 18, 2026

Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. Nithila A is a Dental Surgeon specializing in providing comprehensive oral healthcare. She focuses on preventive care, routine dental treatments, and patient education to maintain optimal oral health. Known for her compassionate and patient-centered approach, she ensures comfortable and effective dental care tailored to the individual needs of each patient.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Prakash. H. M.
Dr. Prakash. H. M.

Hematology

Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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