Thank you doctor,
My local doctor also adviced me to have intravitreal injection anti vegf. Do you think that anti vegf intravitreal injection will be effective as an intravitreal dexamethasone of 4 mg? I am now taking Clindamycin 300 mg four times a day and Sulfamethoxazole Trimethoprim 800 160 mg twice a day, also my doctor put me yesterday on oral Prednisolone 60 mg per day (I am about 80 kg so 0.75 mg per kg). Do you think that I might include Acyclovir for the herpetic suspects?
About the vaccinations for the herpetic diseases- I do not have such vaccinations, so I must have been going through all of them at some time in life - VZV, HSV 1, EBV and CMV. Yet no active IgM found. Toxoplasmosis blood tests are negative. As the doctors did not prove yet what is the actual cause of my uveitis, I am thinking they are just trying to presume one based on how my lesion(s) looks like and where are they located. So and they are presuming toxoplasmosis, but they are not sure, neither I. I was also thinking that EBV might be a potential candidate too, or HSV 1. I missed to mention that I also did a scan of my eye orbits along with the brain scan and nothing found- just my uveities which is also visible with the OCT scans. Back to my recent periocular injection with Triamcinolone- I have read that its extremely risky to apply long acting corticosteroids for toxoplasmosis (not sure about herpeses) as they may lead to uncontrolled acute inflamation. And my vision of the right eye started to worsen after the third week of the injection application and on the fourth week my central vision is now also very poor. How long do you think a periocular injection with Triamcinolone might take to stop acting? It did enough damage already, just hoping that whole mistaken process is stopping. My doctor is saying that it might be just the course of the diseases, but I doubt. My uveitis flared up a week after our summer vacation. I felt a short episode of fever right after doing a bath and I thought that is really strange to be feeling cold shakes as it was extreemly hot. Another wierd thing was that during one of our lunches I felt strong and aproximatly short pain in my upper and lower jaw from the right. Right after already having the uveities flare a day or two after that I was having а fever with a small increase of my body temperature (37.7 to 38 Celsius) for about a week or two. No swelling of the lymph nodes. No rashes after taking the antibiotics.
About myalgia - a week before our summer vacation I was having extreem back pain (at right again). So a local doctor shot me two injections of corticosteroids and few with Milgama (Vitamin B) around where my aches were. Now, I wonder if the corticosteroid injections could be what triggered after two weeks my uveitis. They were applied low right in my back. I did later a scan of my back and a discopathy was discovered at my lower right of spine. No rheumatological were found (I was hospitalized for detailed examination including spine scan and blood tests) as I was not sure if my back pain my be related with the uveitis onset. I do not have other diseases that I know about.