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Is mitral valve prolapse common in Marfan syndrome?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have an abnormal T-wave, high QRS voltage, abnormal QTc, and a pulse of 60 beats per minute. Two readings were taken. Marfan syndrome is present. I am a 33-year-old male with a weight of 180 pounds and a height of 6.1 feet. I also experienced chest tightness, heart palpitations, a fast heartbeat, fluttering, fatigue, and an inverted sternum since birth (the abdominal area protrudes, not due to fat but possibly due to a chest deformity, which is sunken in).

Do you see signs of ischemia, and what could be wrong based on these readings?

Please advise.

Hello,

Welcome to icliniq.com.

I have reviewed the ECG (electrocardiogram) and images (attachment removed to protect patient identity). The abnormally high QRS voltage could be due to the chest wall deformity, which may cause the heart to be closer to the chest wall than usual. As a result, the recording electrodes capture higher voltages from the heart muscle. The QT interval also appears normal. I believe the palpitations could be due to underlying mitral valve prolapse and not ischemia, which is common in Marfan syndrome, as well as aortic root disease. You will need to have an echocardiogram performed to diagnose these conditions.

Thanks and regards.

Medically reviewed byDr. K. Shobana

Published At July 7, 2018
Reviewed AtMay 15, 2026

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