What does the increased signal at C2 and C4 cord indicate?

Question

Hello, doctor,

I have increased signal intensity within the cervical cord at C2 and C4 levels. The cervical discs have degenerated with some loss of normal disc height and hydration. What does this mean? I also have multiple sclerosis. My current medications are Gilenya, Amitriptyline, Omeprazole, and Venlafaxine. In the past, I have been on Lyrica.

Please help.

Answer 1

Hello,

Welcome to icliniq.com.

I would like to know if you have performed any brain MRI (magnetic resonance imaging) studies. These lesions in the cervical spine could be related to many possible causes. They could be MS (multiple sclerosis), cervical myelopathy, myelitis, neuroinfections, etc. The diagnosis of MS should be made based on some specific neurological criteria, including multiple lesions like this in the brain's white matter.

Besides, the diagnosis is also based on the medical history (clinical relapses with neurological deficits that have improved). In such cases, a lumbar puncture would also be necessary. There is also stenosis of the cervical spinal column in such cases at this level. The primary differential diagnosis should be made with cervical myelopathy.

I hope this helps.

Thank you.

Answer 2

Hello,

Welcome back to icliniq.com.

If you have not had these lesions in your previous cervical spine MRI (magnetic resonance imaging), they are likely new lesions. A cervical spine magnetic resonance imaging (MRI) study with Gadolinium enhancement is necessary to determine if it is an active plaque or an old one. In contrast, enhancement, treatment with steroids like Methylprednisolone, would be needed. It would help if you discussed the above issues with your doctor.

I hope this helps.

Thank you.