Nephrotic syndrome occurs when the filtering unit of the kidneys gets damaged. The clusters of small blood vessels in the kidneys are the ones that filter waste and excess water from the blood. This makes the body pass too much protein in the urine. The primary cause of nephrotic syndrome in adults is focal segmental glomerulosclerosis (FSGS).
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My sister has swelling, cushingoid facies and proximal myopathy. Why?
Query: Hi doctor, My sister is 37 years old with previous 2 LSCS. She has symptoms such as swelling over whole body and face. Along with these complaints she has weakness, tiredness, cushingoid facies, proximal myopathy, palpitation, trembling of hands and amenorrhea or slight on and off spotting. She is s... Read Full »
Answer: Hello, Welcome to icliniq.com. I checked your sister's complete details (attachments removed to protect patient identity). She is suffering from relapsing nephrotic syndrome. Her cushingoid facies and proximal myopathy are steroid induced as you must be already knowing.Gradually replacing the steroi... Read Full »
What can I do to improve edema in my feet along with swollen ankles?
Query: Hello doctor, I went for a run a few days back, after which I developed pitting edema with swollen ankles. I had been on Hydrochlorothiazide and steroids for a few weeks with no change. My blood tests and other tests were done, including chest X-ray and ECG. However, my condition is not improving. P... Read Full »
Answer: Hello, Welcome to icliniq.com.I went through your query and understood your concern. I have checked your reports (attachment removed to protect the patient's identity). Lipids show elevated cholesterol. Urinalysis was okay but with some amount of ketone bodies. These changes are more typical of a ... Read Full »
Do birth control pills cause nephrotic syndrome?
Query: Hi doctor, My daughter has been taking birth control pills for five months, since she gave birth. About two months ago, she started having some swelling in her feet and legs. She waited to see if it would go away, but it did not. Her doctor did some tests and found protein in the urine, so she sent ... Read Full »
Dr. Geetha Priyadarsini Kamminana
Answer: Hello, Welcome to icliniq.com. As your physician said, birth control pills do not cause nephrotic syndrome or protein in urine. Nephrotic syndrome is the combination of nephrotic range proteinuria (more than 3 g of protein in urine) with a low serum albumin level and edema. The eti... Read Full »
Does protein leak from the larger filter of kidney in nephrotic syndrome?
Query: Hi doctor, I heard that in nephrotic syndrome the filtering unit of kidney becomes larger and so protein comes in urine. I am a patient of cortisone dependent nephrotic syndrome over 15 years. Doctor says that about 95 percent of children will get cured at the age of 18. I am 17 years old now. When... Read Full »
Answer: Hi,Welcome to icliniq.com.Yes, you have heard the things right. Due to increased pore there is protein in urine. The best treatment remains the Cortisone. In cases where there is no response to Cortisone as evidenced by persistence of albumin in urine, we need to shift those patients on Cyclophospha... Read Full »
In how many days does the swelling due to nephrotic syndrome in a baby reduce?
Query: Hello doctor, My daughter, 2.8 years old was diagnosed with nephrotic syndrome. She had swelling in limbs, private part, stomach, and eyes. She also had slight cold during that time, but no running nose or cough. I have attached her reports. From the last one week, we started medicine, post which ... Read Full »
Answer: Hello, Welcome to icliniq.com. I can see clearly that your daughter’s condition is improving (attachment removed to protect patient identity). This is the nephrotic syndrome of minimal change type as usually comes in the children. The reason behind less improvement in the private area and stomac... Read Full »
There is a pancreatic growth with nephrotic syndrome. Is the growth malignant?
Query: Hello doctor, I am super scared. I am 30 years old and have been in the hospital for nephrotic syndrome which was discovered to be membranous nephropathy. They tested my blood for many conditions which could be a secondary cause including hepatitis and autoimmune and nothing came up. Now, they are ... Read Full »
Answer: Hi, Welcome to icliniq.com. There can be many idiopathic causes of a nephrotic syndrome which respond good to medical management. As far as pancreatic mass is concerned, there are high chances for your mass to be benign lesions. So there is nothing to worry. Follow proper instructions for nephroti... Read Full »
Treatment for losing protein in the urine
Query: Hi doctor, My wife is losing protein in the urine. The result is ++. She usually remains tired and also has pain in some part of the body like back pain or head pain. She also has a lot of black pigmentation marks on her body. Is pigmentation marks cause any serious problem? Can you please tell me ... Read Full »
Dr. Mahmoud Ahmed Abdelrahman Abouibrahim
Answer: Hi, Welcome to icliniq.com. Protein in urine can be due to a nephrotic syndrome which could be due to many causes. Blood pressure, blood albumin level, and random blood sugar should be measured. Her urine test shows some pus cells (attachment removed to protect patient identity). I suggest using ... Read Full »
What is the treatment for focal segmental glomerulosclerosis in a 12-year-old?
Query: Hello doctor, My 12 year old son is suffering from nephrotic syndrome since the last seven years. Two years ago, when his biopsy was done, the result said FSGS. His creatinine levels at that time was 4. Now it is raised to 10.1. He is currently taking Calcium, Folic acid, Pantoprazole, Sodium bicar... Read Full »
Dr. Geetha Priyadarsini Kamminana
Answer: Hello, Welcome to icliniq.com. Please furnish the following medical information, so that I will be able to give you further advice. What is the cause of focal segmental glomerulosclerosis (FSGS)?Has dialysis been done? What is his urine output?What does his antinuclear antibody (ANA) profile say?Has... Read Full »
How is nephropathy related to eyes and ears?
Query: Hello doctor, I am 15-years-old. My native kidney biopsy is: Microscopic description: The sample contains renal cortex, with 21 glomeruli (8 of them globally sclerosed). Some glomeruli reveal mild mesangial matrix expansion, marked glomerular hypertrophy, segmental glomerulosclerosis in 4 glomer... Read Full »
Answer: Hello, Welcome to icliniq.com. I read your query and the biopsy report. Can you tell me what were the kidney functions of the patient (urea and creatinine)? Also, tell me the urine examination of the patient and if 24-hour urine protein was done? Is there any family history of kidney failure? Wer... Read Full »
What does facial swelling and proteinuria in a small kid indicate?
Query: Hello doctor, My baby has swelling in the face lasting for a week. We consulted our family physician and urinalysis showed proteinuria. She is born full-term from her first normal pregnancy. Birth weight is 3040 g, and Apgar score is 9/10. She is breastfed and we observed bloody mucus in feces sinc... Read Full »
Answer: Hello, Welcome to icliniq.com. As per your description and the reports, the child seems to be fitting into the nephrotic syndrome. Steroids will have to be started for the same, along with antibiotic cover for now. However, it is best to get the child evaluated physically by a nephrologist before... Read Full »