Platelet Transfusion

Platelet transfusion is done in patients who have a low platelet count or platelet do not function properly in clotting the blood. It is indicated in patients with reversible bone marrow failure to prevent spontaneous bleeding and low platelet count during dengue.

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What is ITP?

Query: Hi doctor, My nephew has been unwell since few days. Since two weeks, he has small blood patches on thigh, calves and ankles. Petechial rash and bruising are also present. The doctors have diagnosed him with ITP (idiopathic thrombocytopenic purpura). I am writing to you to get a second opinion. He ...  Read Full »


Dr. Geetha Priyadarsini Kamminana

Answer: Hi,Welcome to icliniq.com. Isolated low platelet count with normal hemoglobin and CBC (complete blood count) usually is the key laboratory finding for ITP (idiopathic thrombocytopenic purpura) as there in this case. It is the diagnosis of exclusion however. I need few more details about his medica...  Read Full »

How to increase platelet count during dengue fever?

Query: Hi doctor, My daughter is 8 years old. She has been suffering from fever for five days. Her fever is in the range of 99 to 102 degrees. When we visited a doctor, he asked for a blood test. The blood report shows that she is positive for dengue. The platelet count has dropped already to 52000 from 1,...  Read Full »


Dr. Naresh Kumar Monigari

Answer: Hello, Welcome to icliniq.com. I had gone through the data you have posted. Low platelet count occurs in almost 70% of people with dengue fever. Normally, in case of disease the platelet count may go low for four to five days and then starts rising. Low platelet count (<100000) has risk of bleedi...  Read Full »

My grandmother has a platelet count of 10,000. Will she be alright?

Query: Hello doctor,My grandmother has a platelet count of 10,000. She is currently on her blood pressure medication. Of note, at the age of 52, she was operated on for severe menstrual bleeding. However, there is no sign of cancer in our whole family. Today is her transfusion. Will she be alright? I have ...  Read Full »


Dr. Singh Smrita

Answer: Hello, Welcome to icliniq.com. I have viewed the reports attached (attachment removed to protect patient identity) apart from a punched-out lesion on the skull. There seems to be no abnormality. Generally, a lytic lesion in the bones of an elderly person would raise the suspicion of multiple myel...  Read Full »

Tests for dengue are negative, then why is the platelet count low?

Query: Hi doctor, My father is admitted to the hospital as his platelet count is 8000/cumm. The tests for dengue and NS1 are negative. After injection of 4 units of platelet, his platelet count is 12000/cumm. Then after administering 2 and 4 more units, the platelet count was 23000/cumm and 22000/cumm re...  Read Full »


Dr. Chelladurai Pandian Hariharan

Answer: Hi, Welcome to icliniq.com. This is definitely not normal. Even though dengue antigen is negative, the low platelet count gives suspicion of dengue. The line of management is on the right way. So do not worry. Once the platelet count crosses 25000, we can stop the platelet transfusion. Only freque...  Read Full »

How to cure the brain hemorrhage in my father?

Query: Hello doctor,My father has a brain hemorrhage. He has multiple blood clots. I am attaching the CT scan reports. Please have a look.  Read Full »


Dr. Salah Saad Hassan Shoman

Answer: Hello, Welcome to icliniq.com. These are not blood clots but areas of bleeding within the brain. He should be treated with hemostatic agents till the resolution of the hemorrhage and edema. For more information consult an internal medicine physician online --> https://icliniq.com./ask-a-doctor-on...  Read Full »

What is the normal platelet count and what is thrombocytopenia?

Query: Hi doctor, My platelet count is low for the past month, between 115000 to 130000 platelets per mcL, which I found during my regular body check-up. I do have any previous issues related to this. Please guide me.  Read Full »


Dr. Mubashir Razzaq Khan

Answer: Hi, Welcome to icliniq.com. Your counts are clinically insignificant. Low platelet count is also called thrombocytopenia. In grade 1 thrombocytopenia, platelet count ranges between 75000 to 150000 platelets per mcL. No action is needed. Just follow-up is enough. In grade 2 thrombocytopenia, plat...  Read Full »

Please suggest a treatment plan for platelet disorder.

Query: Hi doctor, My mother is suffering from platelet disorder from the last one month. She had nearly about 58 units of platelet transfusion, but still her platelet count is not up to the mark. What to do further?  Read Full »


Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: Platelet count needs to be maintained around 200000, if there is no bleeding. As I am not sure about the platelet count and the cause of your mother, if this is maintained then it is adequate. Multiple platelet transfusions c...  Read Full »

What is storage pool defect?

Query: Hi doctor, My son has storage pool defect. Now, his doctor suspects Crohn's disease on him. All cut tests will result in horrible bleeding time. Should hematology be involved? Should the doctors use coagulant as a precaution? Your further advice would be helpful. Thank you.  Read Full »


Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: Yes, patients with storage pool deficiency (platelet function disorder) will have increased and horrible bleeding time. We are looking at one of the important bleeding disorder here. Unless they have decided to take a biopsy ...  Read Full »

What is the safe platelet count for surgery?

Query: Hi doctor, I am a 73 year old male and scheduled for a co-surgery. Da Vinci prostatectomy for PC and double hernia repair with patches. My platelet count is 92 x 10^3 per microliter. I have had this for over 17 years. I had a bone marrow biopsy before 16 years and also, had a recent one before 3 y...  Read Full »


Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: Yes, this platelet count is acceptable for all major procedures, except involving the central nervous system. No problem should occur during surgery with this platelet count. However, if doubtful, then can go for extra platel...  Read Full »

My brother's platelet counts are not going up even after transfusion. What to do?

Query: Hello doctor,My brother has dengue fever. His platelet counts were dropping and once they reached 18,000 he was given one unit of platelet transfusion. But, his counts did not increase when checked after four hours and was at 17,000. So, the doctor went for a second infusion. There are no other sy...  Read Full »


Dr. Sagar Ramesh Makode

Answer: Hello, Welcome to icliniq.com. Firstly, do not panic. Dengue is a self-recovering condition. His platelet counts will gradually rise. Platelet transfusion is fine. Normally, random donor platelets (RDP) increases the platelet count by 5000 only while single donor platelets (SDP) increases it by a...  Read Full »

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