My mother has been diagnosed with PUNLMP. Are there possibilities for it to turn malignant and undergo metastasis?

Q. Does a PUNLMP undergo metastasis?

Answered by
Dr. Arshad Hussain Shah
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Dec 10, 2022 and last reviewed on: Dec 13, 2022

Hello doctor,

My mother has been diagnosed with PUNLMP under the medical code M8130/1. She had undergone a surgical procedure in which the neoplasm had been removed, and the tissue was sent for biopsy, which confirmed the diagnosis. Can you tell me what further care steps are required for her from now on? Also, please suggest to me if this is a form of malignant cancer. Is there any possibility that this tumor may undergo metastases?

Please help.



Welcome to

I went through your query and understood your concern.

It is a papillary urothelial neoplasm of low malignant potential (PUNLMP). Removal of the tumor is the only treatment for it. But there is some risk that it can recur again and in very rare cases, it can recur with invasive cancer. However, it is a precancerous lesion and will not recur again. I suggest she consult a urologist regularly for follow-up to prevent and detect any early recurrence.

Also, please provide me with full details of her histopathological report, blood tests, urine analysis, cystoscopy, etc.

I hope this has helped you.

Thanks and regards.

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