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My wife has Raynaud's with pale violet and gangrene fingers. Please help.

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My wife has arthritis and has become very weak over the last few months. Now she has a condition that is more or less like Raynaud's phenomenon. Her fingers are turning pale violet, and one of the fingers has gangrene-like occurrences.

Not only the hands but even the toes are experiencing the same.

Please help.

Thank you.

Answered by Dr. Naval Mendiratta

Education:

MBBS

Professional Bio:

Dr. Naval Mendiratta is a dedicated Rheumatologist with extensive experience in diagnosing and managing autoimmune and musculoskeletal disorders. His expertise includes treatment of rheumatoid arthritis, lupus, vasculitis, and other connective tissue diseases. Dr. Mendiratta focuses on evidence-based care, early diagnosis, and improving patient quality of life through personalized treatment strategies and compassionate, long-term management.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

You are right in saying that she has the symptoms of Raynaud's with digital gangrene, which is ongoing. Arthritis, there are 50 variants of it, and it is very important to distinguish which one she has, as the management will differ for every type of arthritis.

I would like to ask a few more questions:

  1. Is there any history of oral ulcers?
  2. Hairfall?
  3. Any history of fever?
  4. Which joints are affected?
  5. Is there swelling in the joints?
  6. Is there any deformity?
  7. Are there any changes in skin color or skin becoming tighter?
  8. Is there any history of dry eyes or dry mouth?
  9. Is there any muscle weakness that you have observed?

With the start of Raynaud's, it seems like a systemic involvement more, something like lupus, but we need to rule it out. Kindly let me know the answers, and I will advise a few tests. If they have been done, please attach the reports as well.

Thank you.

Patient's Query

Hello doctor,

Thank you for the reply.

I will have the tests done and will upload the reports.

No history of oral ulcers or hair loss. She has thyroid problems on the higher side. No fever and no swelling in joints or deformity. No history of dry eyes or dry mouth, and no muscle weakness.

Please help.

Thank you.

Answered by Dr. Naval Mendiratta

Education:

MBBS

Professional Bio:

Dr. Naval Mendiratta is a dedicated Rheumatologist with extensive experience in diagnosing and managing autoimmune and musculoskeletal disorders. His expertise includes treatment of rheumatoid arthritis, lupus, vasculitis, and other connective tissue diseases. Dr. Mendiratta focuses on evidence-based care, early diagnosis, and improving patient quality of life through personalized treatment strategies and compassionate, long-term management.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

I suggest we get these tests done and sort out which type of arthritis she has. Meanwhile, you can start her on tablet Nifedipine 10 mg twice daily for the Raynauds, as it will help the healing of the tissue as well.

I hope it helps.

Thank you.

Patient's Query

Hello doctor,

Thank you for the reply.

I have attached the file.

Thank you.

Answered by Dr. Naval Mendiratta

Education:

MBBS

Professional Bio:

Dr. Naval Mendiratta is a dedicated Rheumatologist with extensive experience in diagnosing and managing autoimmune and musculoskeletal disorders. His expertise includes treatment of rheumatoid arthritis, lupus, vasculitis, and other connective tissue diseases. Dr. Mendiratta focuses on evidence-based care, early diagnosis, and improving patient quality of life through personalized treatment strategies and compassionate, long-term management.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

I have gone through the reports (attachment removed to protect patient identity). The only report I found was ANA (antinuclear antibody), which is positive at 1:80, and rheumatoid factor, too. But since you mentioned there is no visible swelling in the joints and there is more of Raynaud's, the diagnosis would be more in favor of undifferentiated connective tissue disease.

Although limitations remain to give a complete diagnosis without clinical examination, we are fine to start her with milder medications to prevent the disease from progressing. The diagnosis in her case is undifferentiated connective tissue disease.

I suggest she take the following medications:

1. Tablet Hydroxychloroquine 200 mg twice daily.

2. Tablet Nicardia R (Nifidipine) 10 mg twice daily (for Raynaud's).

3. Capsule Uprise D3 60 K (Cholecalciferol) once a week for eight weeks and then once a month to continue.

Consult your specialist doctor, discuss with them, and take the medicines with their consent.

I hope it helps.

Thank you.

Patient's Query

Hello doctor,

Thank you for the reply.

Answered by Dr. Naval Mendiratta

Education:

MBBS

Professional Bio:

Dr. Naval Mendiratta is a dedicated Rheumatologist with extensive experience in diagnosing and managing autoimmune and musculoskeletal disorders. His expertise includes treatment of rheumatoid arthritis, lupus, vasculitis, and other connective tissue diseases. Dr. Mendiratta focuses on evidence-based care, early diagnosis, and improving patient quality of life through personalized treatment strategies and compassionate, long-term management.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

Keep in touch for further doubts.

Medically reviewed by Dr. Vinodhini J.
Published At May 29, 2020
Reviewed At June 22, 2026

Education:

MBBS

Professional Bio:

Dr. Naval Mendiratta is a dedicated Rheumatologist with extensive experience in diagnosing and managing autoimmune and musculoskeletal disorders. His expertise includes treatment of rheumatoid arthritis, lupus, vasculitis, and other connective tissue diseases. Dr. Mendiratta focuses on evidence-based care, early diagnosis, and improving patient quality of life through personalized treatment strategies and compassionate, long-term management.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Vinodhini J. is a Dental Surgeon with extensive years of clinical experience. She specializes in the diagnosis, prevention, and treatment of dental and oral health issues, including restorative, surgical, and cosmetic procedures. With a patient-centered approach, she focuses on maintaining oral health, alleviating discomfort, and enhancing smiles. Her expertise ensures comprehensive care tailored to each patient’s dental needs and overall wellbeing.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Naval Mendiratta is a dedicated Rheumatologist with extensive experience in diagnosing and managing autoimmune and musculoskeletal disorders. His expertise includes treatment of rheumatoid arthritis, lupus, vasculitis, and other connective tissue diseases. Dr. Mendiratta focuses on evidence-based care, early diagnosis, and improving patient quality of life through personalized treatment strategies and compassionate, long-term management.

This doctor is not available for online consultations on the platform anymore.

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