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HomeAnswersNeurologysevere fatigueI am experiencing extreme fatigue and muscle twitching. Why?

I have pain,extreme fatigue,unsteadiness and muscle twitching.I do not know if all these symptoms are related to one issue or more.


The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Ashok Kumar

Medically reviewed by

iCliniq medical review team

Published At November 7, 2014
Reviewed AtMarch 15, 2024

Patient's Query

Hello doctor,

I have had this problem for 8 years with no proper solutions. Please help. Strange sensations, tiredness, feeling of heaviness in the arms and legs. Hands and feet become warm. I have an electrical shock like feeling in face. I have extreme fatigue, unsteadiness and muscle twitching in the arms and legs and my eye often twitches. Now my feet and hands itch like crazy. Feet are worse than the hands. 

I take Cymbalta, Lyrica and Levothyroxin. I have had MRIs of the spine and brain, nerve conductivity test, and many blood tests including heavy metals, HIV, syphilis, drug test, vitamin levels test, Lyme disease test, ANA and so many others.

The doctors are not able to figure out what is wrong. I had about 25 hours of sleep only this whole week, because I have so much pain. When I do sleep I thrash all over the bed. Going this long without getting much sleep is not normal for me. I usually do get more sleep than this. When all this first started I got very sick, lost weight (about 40 lbs in two months) and laid on the couch for a year missing out on life because I was too exhausted and sick.

I do not know if all these symptoms are related to one issue or more. The doctors thought I had MS, but no lesions. Please help me. Thank you!

Answered by Dr. Ashok Kumar


Welcome to icliniq.com.

I read your query and understand your concerns.

  • This is a disorder which generally occurs in middle age women (I am not aware about your age and gender).
  • It is characterized by pain and stiffness of the soft tissues, such as muscles, ligaments, and tendons.
  • The cervical (neck) and thoracic (chest) areas are affected most often, but the pain may be located in the arms, shoulders, low back, or legs.
  • Pain is also associated with anxiety, fatigue and inability to sleep.
  • The diagnosis is made after excluding rheumatic disease or hypothyroidism.
  • Fibromyalgia is also present in chronic fatigue syndrome and depressive disorders.

If your age and other description does not match with the above narration or if you have more questions feel free to write back to us.

Consult a neurologist online for further help --> https://www.icliniq.com/ask-a-doctor-online/neurologist

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ashok Kumar
Dr. Ashok Kumar


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