Sex Hormone-binding Globulin

Sex Hormone-binding Globulin (SHBG) is a protein synthesized by the liver which readily attaches to the sex hormones found in both men and women. These include Testosterone and Dihydrotestosterone found in males and Estradiol found in females. SHBG limits the number of hormones presented to the body. Although it binds to all three hormones, this test is used to detect the testosterone used by the body.

Recently Answered Questions Recently Answered Questions

All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

Do my test results correlate with my hair loss?

Query: Hi doctor, I have substantial focal hair loss. Three blood tests have been taken, and the results are high in SHBG, but normal levels of testosterone. I am not on the contraceptive pill or any other medicine aside from DHEA, which was recently prescribed. DHEA low and proteins are also low. Is there...  Read Full »


Dr. Sadaf Mustafa

Answer: Hello, Welcome to icliniq.com. Do you have normal DHT (dihydrotestosterone) and estrogen levels? I am asking this since you have elevated SBG (sex hormone-binding globulin). You can have hair loss with excess DHT or estrogen. Revert with the details to an internal medicine physician online --> h...  Read Full »

What does low testosterone and high SHBG indicate?

Query: Hello doctor,I got bloodwork done for possible low T.My SHBG is higher, out of the normal range, even though the rest of my blood work is very good to excellent. My doctor told me that this is uncommon. I am curious as to how concerned I should be about this?  Read Full »


Dr. Shaikh Sadaf

Answer: Hello, Welcome to icliniq.com.I read your query and seen your lab reports. (attachment removed to protect patient identiy).Your report does suggest some concerning things such as high creatinine and low GFR (glomerular filtration rate), which suggest kidney dysfunction and a high SHBG (sex hormone b...  Read Full »

How to know the reason for low testosterone?

Query: Hi doctor, I am 34 years old. My weight is 84 kg. I am married for four years. I am unable to make a relationship with my wife. The erection problem is there for the past two years. I checked my testosterone level, which is 183. Why is it low? Please advise me the ways to increase the testosterone l...  Read Full »


Dr. Divakara P

Answer: Hi, Welcome to icliniq.com. Your testosterone is quite low. We first need to find the cause of that. In that regard, I recommend the following tests to you. FBS (fasting blood sugar), PPBS (postprandial blood sugar), SHBG (sex hormone-binding globulin), TSH (thyroid-stimulating hormone), serum pro...  Read Full »

What can cause less dense beard?

Query: Hi doctor, I am a 23 year old male. My height is 5'8" and weight is 63 kg. I am currently not using any kind of medicine. My beard is not growing completely and I notice less growth on my mustache. Please help me.  Read Full »


Dr. Atishay Bukharia

Answer: Hi, Welcome to icliniq.com. There are two main causes of decreased beard hairs: Genetic.  Hormonal imbalance. We cannot do anything more in genetics case, but we definitely can rectify the endocrinology cause. So, you need to go for a few investigations such as serum free testosterone, serum DHEAS ...  Read Full »

Am I suffering from Klinefelter syndrome?

Query: Hello doctor, I am an 18 year old, who weighs 95 kg, and I am obese. I have small testicles and penis. My testosterone level is 7.8. The test was done at 9 AM. I have very less body hair, little hair on my legs, and a lot of pubic hair. I have less beard growth and no hair in the armpits. I am con...  Read Full »


Dr. Shaikh Sadaf

Answer: Hello, Welcome to icliniq.com. I just read your query and saw your detailed reports (attachment removed to protect patient identity) and from the history that you mentioned, it does seem that you might be possibly having Klinefelter syndrome but, there are some tests which are not confirming your di...  Read Full »

ask-doctor-img Ask a Doctor Online

* guaranteed answer within 4 hours

Search for a Health Issue



Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.