Common "Sex Hormone-binding Globulin" queries answered by top doctors | iCliniq

Sex Hormone-binding Globulin

Sex Hormone-binding Globulin (SHBG) is a protein synthesized by the liver which readily attaches to the sex hormones found in both men and women. These include Testosterone and Dihydrotestosterone found in males and Estradiol found in females. SHBG limits the number of hormones presented to the body. Although it binds to all three hormones, this test is used to detect the testosterone used by the body.

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Do my test results correlate with my hair loss?

Query: Hi doctor, I have substantial focal hair loss. Three blood tests have been taken, and the results are high in SHBG, but normal levels of testosterone. I am not on the contraceptive pill or any other medicine aside from DHEA, which was recently prescribed. DHEA low and proteins are also low. Is there...  Read Full »


Dr. Sadaf Mustafa

Answer: Hello, Welcome to icliniq.com. Do you have normal DHT (dihydrotestosterone) and estrogen levels? I am asking this since you have elevated SBG (sex hormone-binding globulin).You can have hair loss with excess DHT or estrogen.   Read Full »

What are the symptoms of Klinefelter syndrome?

Query: Hello doctor, I am an 18 year old, who weighs 209.4 lbs, and I am obese. I have small testicles and penis. My testosterone level is 7.8.The test was done at 9 AM. I have very less body hair, little hair on my legs, and a lot of pubic hair. I have less beard growth and no hair in the armpits. I am co...  Read Full »


Dr. Shaikh Sadaf

Answer: Hello, Welcome to icliniq.com. I just read your query and saw your detailed reports (attachment removed to protect patient identity) and from the history that you mentioned, it does seem that you might be possibly having Klinefelter syndrome (KS) but, there are some tests which are not confirming y...  Read Full »

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