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Are there any liver supplements I can take while on Risperdal and Depakote?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

Are there any liver supplements that I can take while on Risperdal and Depakote?

Answered by Dr. Surabhi

Hi,

Welcome to icliniq.com.

The side effects of Depakote (Sodium valproate) on the liver are quite common and well known. It does cause an increase in liver enzymes level and symptoms like weakness, lethargy, jaundice (yellowing of skin and sclera), loss of appetite - all due to its effect on the liver.

But, there is no role of any liver supplements to prevent Depakote-induced liver dysfunction. What you can do is get liver function tests (LFT) done regularly and check for an increase in liver enzymes. Only if the value is at least three times the normal, the medication can be stopped.

For a detailed reply, kindly give more details regarding your illness as well as the current medications.

For more information, consult a general practitioner online.

Answered by

Dr. Surabhi

Medically reviewed byiCliniq medical review team

Published At October 17, 2014
Reviewed AtMay 6, 2025

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Surabhi

Dr. Surabhi

Psychiatry

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