Common "Sulfasalazine" queries answered by top doctors | iCliniq


Sulfasalazine is an anti-inflammatory drug sold under the brand name Azulfidine. Rheumatoid arthritis, ulcerative colitis, and Crohn's disease are all treated with Sulfasalazine. It works by reducing inflammation in the body. Some of the common side effects of this drug include; diarrhea, nausea, heartburn, abdominal pain, dizziness, cough, pain in the joints, etc.

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Which MRI will best reveal spondyloarthropathy?

Query: Hello doctor, I am a 31-year-old male, and I was diagnosed with spondyloarthropathy seven years back. I am taking only Sulfasalazine tablets daily. Currently, I do not have any pain or stiffness. My HLA-B27 report is negative. Now, if I do the following MRIs, what chances are there that any abnormal...  Read Full »

Dr. Naval Mendiratta

Answer: Hello, Welcome to I am unable to find the attachment. It is good to know that you are doing well on Sulfasalazine only. But if you are doing well and have no symptoms with normal blood tests, I will not recommend MRI (magnetic resonance imaging) to be repeated. The MRI is only needed ...  Read Full »

I am suffering from ankylosing spondylitis. Kindly help.

Query: Hello doctor,I am suffering from ankylosing spondylitis (HLA B27 positive and Rh factor negative) for 10 years, now on Saaz-DS, SI joints are fused. Movement restrictions of the neck, forward bending, and morning stiffness with sciatica. Kindly suggest new medications and NSAIDs. I have attached HLA...  Read Full »

Dr. Puri Divya Inder

Answer: Hello, Welcome to The NSAIDs you can take are Etoricoxib 90 mg once daily orDiclofenac75 mg twice daily. You can try this out and see which one helps more. Once your pain is controlled, you can try to reduce the dose to alternate days or even lesser depending on your pain. Folic acid ...  Read Full »

I suffer from pain in my joints despite taking medications. Why?

Query: Hello doctor, I am a 36-year-old, male, height 160 cm, and weight 52 kg. I am suffering from an autoimmune disease, for the last 20 years. 13 years ago, I took Methotrexate 7.5 mg to 12.5 mg and got fully recovered. Later again 10 years back I got the same issue, and the same doctor prescribed Sulfa...  Read Full »

Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to You need to remember that Sulfasalazine is a very weak drug and does not show much response. Methotrexate is good but takes about six weeks to start acting and show response. I would suggest a short course of steroids Methylprednisolone 4 mg once a day for 10 days a...  Read Full »

My wife has Sjogren's syndrome and takes Sulfasalazine. Advise.

Query: Hi doctor, My wife has had Sjogren's syndrome and related rheumatoid arthritis for about ten years. She has been experiencing a flare for five months now, which has migrated from her knees to her heel and hands. She is nearing 70. She is currently on tablet Sulfasalazine 500 mg, two in the morning a...  Read Full »

Dr. Sugreev Singh

Answer: Hi,Welcome to can understand your concern.It differs from person to person. Some people have a higher risk, while some do not. But since she has Sjogren's, I would suggest you continue with the same medicine and take precautions for COVID. Even if she stops the medication, there are ch...  Read Full »

I have had ankylosing spondylitis for 14 years. Please help.

Query: Hello doctor, I have ankylosing spondylitis (HLA B27 positive) for the past 14 years. After I had COVID six months back while recovering, I had a dull pain in the sternum and cartilage of the chest. I took antibiotics, and the pain subsided. But now, for the past few weeks, while sleeping, it is pai...  Read Full »

Dr. Nupoor Acharya

Answer: Hello, Welcome to The symptoms suggest active disease at present. You are currently on a low dose of tablet Sulfasalazine (anti-inflammatory) which can be increased if needed. To control the inflammation, I suggest taking tablet Etoricoxib (non-steroidal anti-inflammatory drug) 120 mg...  Read Full »

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