For uncontrolled diabetes, is Glycomet-GP2 better than Glycomet-GP3?

Q. For uncontrolled diabetes, is Glycomet-GP2 better than Glycomet-GP3?

Answered by
Dr. Vivek Chail
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jan 03, 2018 and last reviewed on: Jun 14, 2023

Hi doctor,

I am a medical student doing my internship. My father has been suffering from fever since seven days up to 101 F. I have given him Ofloxacin 200 mg two times a day. But, the cause of the fever is unknown. All the blood reports are negative. He is a known diabetic since 20 years and his blood sugar is not under control. His fasting sugar level is 200 mg/dL and after meals 400 mg/dL. He was taking Insulin two times a day in the morning and at night. Since his sugar is not under control he is taking it thrice a day now. I have decided to give Metformin 500 mg with insulin in morning and Glycomet-GP two during lunch and Insulin as well as Metformin 500 mg in the night. Sugar level is getting controlled to 108 mg/dL fasting and 256 mg/dL after food in the morning but in dinner before food it comes to 333 mg/dL . I have decided to change to Glycomet-GP 3. I need your opinion. Please tell me which antibiotic to be given for fever? And which anti-diabetic to give to control blood sugar? Thank you.



Welcome to

If your father is having continuous fever for seven days with negative blood reports then probably a detailed evaluation is required. Tablet Ofloxacin is a broad spectrum antibiotic against most bacterial infections and if his fever is not improving and blood culture and sensitivity is not showing any organism then probably he is having a parasitic infection or a viral infection. Antibiotics should be changed only after repeating blood culture and sensitivity and if there are organisms growing. This is to be discussed with complete clinical examination. Certain tests for infections like malaria and dengue might not show in initial reports and detailed repeat testing is necessary. Typhoid, which is a bacterial infection, is also elusive in early stages and antibody testing might help. Tablet Ofloxacin is a recommended medicine for typhoid and if tests confirm it then he might require a longer course. For blood sugar to control, he should get HbA1C (glycated hemoglobin test) test done once every 3 months to know the average blood glucose which he is having. During illness, he might be switched on to Insulin on sliding scale. This must be done carefully. Infections usually cause high levels of blood glucose in patients. His meal timings must also be maintained and a sample diet like the one given below might help. Early morning: A cup of tea or milk with 2 biscuits of his choice (no sugar), breakfast: Two parathas with curd or 2 plain rotis with paneer or two idlis with chutney or sambhar or 1 bowl of upma or oats, mid morning: Give him soup or a whole fruit either apple or guava, lunch: Salad with rotis (2 to 3) or rice (1 bowl) with dal or sambhar and a cup of vegetable. Occasionally, you can add some light fries in lunch. You can add two vegetables every day, evening: tea or juice with 2 biscuits without sugar, and dinner should be same as in lunch with slight variation. Dinner should be lighter than lunch. You can give one glass of milk without sugar just before going to bed. You might hold the decision to give tablet Glycomet-GP 3 (combination of Glimepiride and Metformin) after observing his blood sugar for two to three days at night before dinner. Anyway, he is on Insulin and tablet Metformin 500 mg at night and this should be able to control the blood glucose to certain extent. Stress him on having a regular diet plan. You have not mentioned any thing about his diet and it is suggested that he follows a strict diabetic diet given above and his blood sugar is monitored at the same time every day. In conclusion, please have a discussion with his treating doctor and get any specific tests done to confirm a suspected clinical diagnosis. Any change in antibiotics can be done only after close clinical evaluation. I hope you have done complete blood count and peripheral blood smear. Doing other basic investigations like chest x- ray and ultrasound scan abdomen might also help. I hope this helps. Thank you and take care. Regards.

The Probable causes:

The probable cause is a parasitic, viral, or occult bacterial infection.

Investigations to be done:

1. Please have a discussion with his treating doctor and get any specific tests done to confirm a suspected clinical diagnosis.

2. Any change in antibiotics can be done only after close clinical evaluation.

3. Get a complete blood count and peripheral blood smear done.

4. Chest x- ray.

5. Ultrasound scan of abdomen.

Treatment plan:

1. Confirm the diagnosis of fever with specific tests.

2. Antibiotics to be changed after isolating organism and doing culture and sensitivity.

3. Diet should be strictly followed.

4. Close monitoring of blood glucose level to be done at specific time every day.

Regarding follow up:

Revert back after investigations to a general practitioner online.

Hi doctor,

He is on strict diet since 10 years. After stroke in brain, he does not have any fat items and no meat also. Only he has vegetarian item with little oil and masala. Please tell the medication to control blood sugar. Now I am planning to change to Glycomet-GP3 only during lunch. Please prescribe me medicine to control sugar. Also tell me if I need to make any change in recent medication. He is unable to sleep at night and taking Lorazepam 2 mg. Kindly suggest me a better Benzodiazepine to get good sleep.



Welcome back to

It is good to know that your father follows a strict diabetic diet and does not take much of fat, oil and masala. Please continue with it and make additions as mentioned earlier. The blood sugar is usually elevated higher than normal during periods of illness. Regarding his medicine for diabetes, you might try and give him tablet Glycomet-GP 3 at lunch and observe his sugar levels. Tablet Glycomet-GP 3 contains Glimepiride 3 mg and Metformin hydrochloride 850 mg and might be able to control blood sugar better than tablet Glycomet-GP 2. There is another higher medicine tablet Glycomet-GP 2 forte. But, that is not required right if his sugar is under control with tablet Glycomet-GP 3. Tablet Temazepam, a benzodiazepine, which can be given in place of Lorazepam. This is to be strictly taken under direct recommendation of a psychiatrist. It might require dose calculation depending on the kidney function. I hope this helps. Thank you and take care. Regards.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
Do I also need benzodiazepine to control my anxiety problem?

.. Zoloft (Sertraline) decreased? Were you facing some side effects? In my opinion, Zoloft is an SSRI (selective serotonin reuptake inhibitor) class of drugs which is one of the best anti-anxiety and antidepression medicines.   Read full

Please suggest a diet chart so that I can study properly and stop gaining weight.

Please help me with some diet charts so that I can study properly and due to improper diet my weight increased alarmingly ... Accordingly, I can suggest a diet chart   Read full

I get anxiety and panic attacks. Will Benzodiazepines help in this regard?

.. panic attacks are extremely common and 15 to 20 percent of people suffer from this issue at some point in their lives. Standard treatment for anxiety is the use of SSRI (selective serotonin reuptake inhibitor) type of medicines.   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

PCOS and Liver Problems
The hormonal imbalances in polycystic ovary syndrome could cause liver diseases. Read the article to know the relationship between these medical conditions.  Read more»
Inferior Alveolar Nerve Lateralization Technique
The inferior alveolar nerve lateralization technique is a surgical lateralization technique to reposition the nerve. Read the article to know more about this.  Read more»
COVID-19 and Ebola: Similarities and Differences
This article gives a comparison and broader overview of the outbreak of the two deadliest diseases that showed a greater incidence over the last two decades.  Read more»

Ask your health query to a doctor online?

Ask a General Practitioner Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.