Patient's Query
Hello doctor,
I am a 30-year-old woman who has been experiencing red, itchy welts daily for the past two weeks. My CBC and thyroid profile were normal, but my serum IgE level was elevated at 360 IU/mL. Antihistamines provide temporary relief.
I am unsure about the trigger. Could this be related to stress or food?
Would allergy testing or an autoimmune screen be functional?
Please help.
Thank you.
Hello,
Welcome to icliniq.com.
I have gone through your query and understand your concern.
You have already taken some necessary first steps by getting lab work done and trying antihistamines, which gives us useful clinical information. The elevated IgE (immunoglobulin E) level of 360 IU/mL strongly suggests an allergic or hypersensitivity reaction. While stress can certainly aggravate symptoms, it is less likely to be the only cause when IgE levels are this high.
In most cases, such reactions are triggered by factors such as new medications or supplements, food allergens, environmental exposures like dust mites, pets, or pollen, recent viral or bacterial infections, or contact allergens, including new skincare products, detergents, or jewelry.
It is helpful to reflect on the past two to four weeks and consider whether you have started any new medications, such as antibiotics or non-steroidal anti-inflammatory drugs (NSAIDs), added supplements, changed your skincare or laundry products, or introduced any new foods.
To better identify a trigger, keeping a symptom diary over the next week can be very valuable. Try to note the time the welts appear, what you ate that day, any products you used, your stress level, and the location of the welts, such as the face, arms, or trunk. This often provides clearer clues than testing alone.
Regarding treatment, if over-the-counter antihistamines like Cetirizine or Loratadine provide only temporary relief, your doctor may advise non-sedating second-generation antihistamines at higher doses, sometimes up to four times the usual dose, which is generally safe and effective for chronic urticaria (a skin condition with itchy welts (hives) and/or swelling (angioedema) lasting over six weeks).
In some patients, adding a medication such as Famotidine to the regular antihistamine can further improve symptom control.
I hope I have answered your question.
Let me know if I can assist you further.
Thank you.
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Answered byDr. Kanishka Sharma
Medically reviewed byiCliniq medical review team
Same symptoms don't mean you have the same problem. Consult a doctor now!
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