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Can I take vitamin B12 supplements with calcium tablets?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My doctor prescribed Steadycal K27 (Calcium Citrate, Calcitriol, and Menaquinone-7) in the morning and at night, along with vitamin D once a week for the next four weeks. A lab test done afterward showed that my vitamin B12 level was also low, under 100 pg/mL.

Can I also take Renerve Plus (Methylcobalamin, Pyridoxine Hydrochloride, and Nicotinamide) with these tablets?

Please help.

Thank you.

Answered by Dr. Kanishka Sharma

Education:

MBBS

Professional Bio:

Dr. Kanishka Sharma is a dedicated general practitioner committed to healing both hearts and minds. She believes the best doctors offer their compassion before their prescriptions, and she strives to provide care that is gentle, thorough, and truly patient-centered. Her approach blends medical knowledge with empathy, ensuring every patient feels heard and supported.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I have gone through your query and understand your concern.

Sure, you can definitely take a tablet containing Methylcobalamin, Alpha lipoic acid, Folic acid, and vitamin B6 together with a tablet containing calcium, vitamin K2, and vitamin D3, and your weekly dose of vitamin D.

Nevertheless, taking into account the low level of your vitamin B12 (less than 100 pg/mL), which means a very severe deficiency, Renerve Plus (Methylcobalamin, Alpha lipoic acid, folic acid, and vitamin B6) may not be sufficient.

It usually includes 750-1500 mcg (micrograms) of Methylcobalamin, which is useful in case of mild deficiency, while in case of severe deficiency (less than 100), the high-dose injections of vitamin B12 (for instance, 1000 mcg IM or intramuscularly, once a day or once a week) are used first, and then the oral forms.

Before starting Renerve Plus (Methylcobalamin, Alpha lipoic acid, Folic acid, and vitamin B6), it is best to check with your doctor to confirm the dose and rule out causes of vitamin B12 deficiency, such as pernicious anemia or dietary issues.

Please answer the following questions:

  1. Do you have any numbness, tingling, balance problems, memory changes, or tongue soreness?

  2. Are you a vegetarian or a vegan?

  3. Any history of gastric surgery or long-term antacid use?

  4. Have you been tested for pernicious anemia or intrinsic factor antibodies?

I hope you are satisfied with my answer. For further queries, you can consult me at iCliniq.

Thank you.

Patient's Query

Hello doctor,

Thank you for the reply.

Yes, I have vertigo, but I have not had an attack in the past two years. However, I do have balance problems while walking for a long time. I also experience numbness in my hands and legs while sleeping. I do not have memory changes or tongue soreness, although I have a long-standing skin infection around the groin area.

I am a non-vegetarian, but my consumption is very low. I have no history of gastric surgery or antacid use. I have not been tested for those conditions.

Please help.

Thank you.

Answered by Dr. Kanishka Sharma

Education:

MBBS

Professional Bio:

Dr. Kanishka Sharma is a dedicated general practitioner committed to healing both hearts and minds. She believes the best doctors offer their compassion before their prescriptions, and she strives to provide care that is gentle, thorough, and truly patient-centered. Her approach blends medical knowledge with empathy, ensuring every patient feels heard and supported.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

I have gone through your query and understand your concern.

Balance problems, especially with prolonged walking; numbness in the hands and legs while sleeping; and tongue soreness are all consistent with possible vitamin B12 deficiency affecting the nervous system. Subacute combined degeneration of the spinal cord can occur in severe cases, although that usually causes more than just balance issues.

Vertigo without recent attacks may or may not be related. Vitamin B12 deficiency can cause unsteadiness, but true rotational vertigo is less typical.

While the skin problem in the groin area, probably a fungal infection like tinea cruris, is not necessarily related to vitamin B12 deficiency, inflammation may have an influence on nutrition in general, or this may just be coincidental.

Vitamin B12 deficiency can result from insufficient intake of non-vegetarian food even in the absence of gastric surgery and antacids.

Now tell me.

  1. When you wake up with numbness in your hands or legs, does it go away within minutes after moving, or does it last for hours or days?

  2. Is it just pins and needles, or a complete loss of feeling?

  3. Regarding balance while walking, do you feel as if you are walking on uneven ground or cotton, or is it more that your legs feel weak?

  4. Do you need to look at your feet to walk steadily, especially in dim light?

  5. For skin infection, has this been diagnosed by a doctor, such as fungal, yeast, or bacterial?

  6. Are you using any regular creams or oral medicines for it?

Some antifungal medicines are very safe, but it is good to know.

I hope I have answered your question.

Thank you.

Medically reviewed by iCliniq medical review team
Published At June 22, 2026
Reviewed At June 29, 2026

Education:

MBBS

Professional Bio:

Dr. Kanishka Sharma is a dedicated general practitioner committed to healing both hearts and minds. She believes the best doctors offer their compassion before their prescriptions, and she strives to provide care that is gentle, thorough, and truly patient-centered. Her approach blends medical knowledge with empathy, ensuring every patient feels heard and supported.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Kanishka Sharma is a dedicated general practitioner committed to healing both hearts and minds. She believes the best doctors offer their compassion before their prescriptions, and she strives to provide care that is gentle, thorough, and truly patient-centered. Her approach blends medical knowledge with empathy, ensuring every patient feels heard and supported.

This doctor is not available for online consultations on the platform anymore.

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