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The Pupil of Our Eye and Problems Related to Its Size

Author: Dr. Manjunath Natarajan - Eye Health  

The pupil is an opening in the center of a muscular diaphragm, the iris. This unique property of iris musculature to contract and hence shrink their size gives the pupil the characteristic property to widen or constrict in size. This plays a very important role in improving the quality of the image we see by reducing the scattering of excess light and by preferentially letting light oriented in the same angle to the orientation of the light receptors in our eye called rods and cones.

The normal size of the pupil is 3 to 4 millimeters in both eyes. A variation of 2 mm between the 2 eyes is considered normal. That means, even if one eye of a patient has a bigger or smaller pupil by 2 mm, it does not necessarily mean that s/he has some ocular problem. The same applies to both eyes.

The process of control of the size of the pupil is done by nervous control. The arm of the nervous system responsible for this is the autonomous nervous system. This essentially means that the size of our pupils is not in our hands but under autonomic nervous feedback control. The center of this reflex is placed in the Edinger-Westphal nucleus in the midbrain and is relayed through the third cranial nerve and its branches. It is thus implied that any injury or lesions involving the cranial cavity, midbrain or third nerve will produce pupillary abnormalities.

The procedure of testing the pupil is fairly simple and is done by using a torchlight, preferably a pen torch. The light causes a constriction of both pupils in a normal patient when shone on one eye. This is because of the shared nervous supply, also called in medical terms as crossing over of internuncial fibers. The attribute of a brisk and comprehensive contract encompassing the whole of the pupil is considered normal.

External Factors Apart from Light Which Play a Role in Constricting the Pupil

These include -

  • Drugs - Medications including certain prescription drugs. For example, cholinergic drugs, also in case of abuse of recreational drugs like morphine and other opioids.
  • Near work - During near work, another nervous reflex called accommodation, comes into play and helps us in focusing on near objects and words while reading.
  • Emotional responses - profound emotions such as crying can cause changes in pupil size including constriction.
  • Ciliospinal reflex - it is also a nervous reflex. Here, the stimulation of skin over the neck causes pupillary constriction. This is also seen in normal individuals.
  • Similarly, diseases causing constriction of the pupil include injury to the iris, tumors in the brain, and third cranial nerve paralysis commonly. Numerous ocular diseases and ocular inflammation can cause pupillary constriction, for example, uveitis. The pupil also undergoes constriction progressively in old age as a process of ageing, accompanied by a loss of tissue elasticity.

External Factors Which Play a Role in the Dilatation of the Pupil

These include -

  • Drugs - Atropine, Homatropine, and Phenylephrine.
  • Caffeine - Coffee intake in normal individuals.
  • Recreational drugs like cocaine.
  • Emotional states - This is especially seen in “fight or flight” situations. For example anger, and fear.
  • As a normal response to low levels of lighting.
  • Similarly, diseases causing dilatation of the pupil include neurological problems such as Adie’s syndrome, Argyll Robertson’s pupil, Horner's syndrome, etc. It can also be seen in injury to the eyeball and in particular, the iris.

Problems Seen in Patients with Dilated Pupils

Although people having constricted pupils have almost no problems with daily activities, the same cannot be said of patients with dilated pupils. As mentioned earlier, pupil plays an important role in vision by regulating the amount of light entering the eye, thus preventing scattering of light and a drop in vision. Thus dilated pupils can cause problems like glare and an aversion to bright light (called photophobia).

Treatment Measures for Dilated Pupils

  1. The main treatment mode is the treatment of the underlying causative disease. A visit to the ophthalmologist will facilitate this.
  2. Good quality sunglasses, preferably with UV/ polaroid filters.
  3. Brimonidine - this is a prescription medication originally intended for lowering intraocular pressure inside the eye. It has been found to reduce pupil size in several studies.
  4. Using indoor car lighting to reduce the amount of glare while driving at night.

For more information consult an eye care ophthalmologist online --> https://www.icliniq.com/ask-a-doctor-online/eye-care-ophthalmologist

Image: The Pupil of Our Eye and Problems Related to Its Size Last reviewed at: 11.Sep.2018

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What are the treatment options available for dilated pupil?
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Answer: Hi, Welcome to icliniq.com. After blunt trauma, pupil constrictor muscles may be damaged and that causes permanently dilated pupil called traumatic mydriasis. This just causes mild blurring or photophobia in bright light due to large aperture. But, in case of trauma, there are more important thin...  Read Full »
 
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Answer: Hello, Welcome to icliniq.com. I think he has aniridia. I am sorry, but there is no permanent cure for this. But yes, you can try cosmetic contact lens, which will decrease photophobia. If his retina is fine, then this will help him. Regards. For more information consult an eye care ophthalmologist...  Read Full »
 
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Answer: Hello, Welcome to icliniq.com. This difference in pupil size is known as anisocoria. There are many causes for anisocoria like the unilateral use of dilating eye drops, Horner's syndrome (disrupted nerve pathway from the brain to face and eye), Adie's pupil (dilated pupil), etc. Kindly consult your ...  Read Full »
 
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