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Kidney and Urologic Diseases Data Verified

How to decrease the Level of Creatinine in the Body?

Written by
Dr. Vidhi Talati Joshi
and medically reviewed by iCliniq medical review team.

Published on Apr 11, 2017 and last reviewed on Jun 14, 2021   -  7 min read

Abstract

A high level of creatinine in the body indicates some problem with the kidneys. Please read the article to know the various treatment options to lower creatinine levels.

Contents
How to decrease the Level of Creatinine in the Body?

Creatinine Gives an Idea About Renal Health:

Serum or blood creatinine gives an idea about renal health. Creatine phosphate is made with three different types of amino acids such as arginine, glycine, and methionine. It is useful to provide energy supply to muscles.

Creatinine is an end product of the creatine phosphate molecule. It is a type of waste product that is released in the blood due to exercising the skeletal muscles. It is actually produced from creatine. Each and every day, some amount of creatine is transferred into creatinine. Its value is approximately 2 % every day. Creatinine is a very harmful product for our body, and that is why its elimination from the body is necessary. Blood creatinine is transported to the kidney, and the kidney excretes this product through urine from our body. That is why kidneys play an important role in the filtration of the blood.

The concentration of creatinine is important in the diagnosis of various kidney-related disorders. It provides an idea about the normal function of kidneys. If kidney function is impaired, there will be an alteration in the amount of creatinine from the normal value. If the kidney fails to eliminate creatinine, the concentration of the creatinine will be high and sometimes cause kidney failure. So, it is a wise decision to take blood and urine tests prior to giving treatment for any disease. Sometimes, the patient is asymptomatic with high creatinine concentration.

Normal Values of the Creatinine in Blood:

The normal value of creatinine is measured in milligrams (one thousand part of the gram) per dl of the blood (one-tenth part of one liter).

Any value above this may indicate a severe kidney disorder or malfunction. More creatinine concentration in infants or babies such as above 2.0 or more than 10.0 in an adult may need dialysis. It is widely used in the emergency department of hospitals.

Creatine is formed in the liver. After formation, it is transported to various organs or muscles, or brains. After reaching a particular site, it reacts with phosphate and makes phosphocreatine. During any activity, this creatine and phosphocreatine are broken down by the creatine kinase enzyme. This also converts all compounds into creatinine and releases them into our bodies. There is always some alteration in the value there. Young and muscular adult men have a higher concentration of creatinine than older ones. Sometimes, malnourished or undernourished persons, amputation (removal of one or more extremities), less muscle mass, severe weight loss may have less concentration of creatinine in the blood.

Causes of Raised Creatinine Levels:

There are some cases related to high creatinine levels in the blood. They are,

  1. Disorders of kidneys.

  2. A family history of kidney disease.

  3. Autoimmune disease.

  4. High blood pressure.

  5. Diabetes mellitus.

  6. Thyroid disease.

  7. Dietary factors - Some food products also contain a high amount of creatinine, such as,

  1. Certain medications - Some drugs are also responsible for a high concentration of creatinine, as those drugs decrease the elimination of creatinine through urine. They are,

Its concentration is measured from urine after 24 of urine collection.

  1. Blocked urinary tract.

  2. Strenuous exercise.

  3. Some diseases can affect kidney function and raise creatinine levels. They are,

Symptoms of Raised Creatinine Levels:

When you come to notice these symptoms, you may need a creatinine test.

  1. Increased urinary frequency.

  2. Fatigue.

  3. Swelling of the feet.

  4. Foams in the urine.

  5. Muscle cramps.

  6. Pain during urination.

  7. Muscle cramps.

  8. Ankle edema.

  9. Blood in the urine.

Harmful Effects of High Concentration of Creatinine in Our Body:

What Are the Treatment Options to Lower the Creatinine?

1) Diet Plan:

A higher concentration of creatinine is due to a disorder of the kidney. So, it is better for us to decrease the load upon the kidneys. The kidney acts to maintain the normal balance of water and electrolytes in our body. Some modifications in the diet are necessary, such as a reduction of intake of protein, phosphorus, potassium, and sodium.

A low protein diet is recommended to reduce creatinine levels. The person should reduce the intake of water or fluid also. Restriction of sodium reduces the pressure of the blood as well as reduces the chances of peripheral edema. The person should be restricted from eating high potassium-containing dietary supplements such as tomatoes, potatoes, nuts, and chocolates. The person should be restricted from eating high concentrations of phosphorus food supplements such as dairy products, including milk, curd, cheese, shellfish, nuts, pork, soybean foods, etc.

The daily requirement of the protein for an adult is 1 gram per kilogram body weight per day. A child and pediatric age group need more protein as compared to adults because protein is an essential element for bone growth. People should avoid sodium-rich foods such as salt, baking soda, cured meat and fish, cheese, pickles, instant soups, roasted and salted seeds, nuts, snacks, fast food such as egg products, and ham biscuits, canned vegetables, etc.

There are many varieties of fruits and vegetables that are advised for kidney diseases. They are:

2) Medication:

Ketosteril is mainly used for the treatment of various disorders of the kidney. Its beneficial effects are a thousand times more than a low protein diet. It is mainly used for reducing the concentration of creatinine in the blood. It supplies the proper amino acids and reduces the formation of creatinine and urea.

3) Dialysis:

When diet and medication do not provide any beneficial effects, dialysis is the last option to eliminate the high concentration of creatinine. Doctor measures the creatinine level and blood urine nitrogen level to test the efficacy of the kidney function. If they are increased above normal, dialysis is a must to remove them.

A health professional collects and saves the urine of a patient for one whole day in an air-tight container. After that, the pathologist may check the concentration of this element in urine and blood. Measurement of creatinine clearance is essential for getting an idea about kidney function.

Creatinine clearance is measured as the difference between blood creatinine and urine creatinine level. If creatinine clearance is below 10 cc per minute, dialysis is a must.

Procedure - There are mainly two types of dialysis, namely peritoneal dialysis and hemodialysis. But for clearance of creatinine, hemodialysis is widely used.

4) Hemodialysis:

In this procedure, one connection is made between the artery and vein of the arm or leg. One catheter is inserted into this connection. Blood coming from the artery goes into the dialysis machine via a plastic tube that is attached to the catheter. Blood is filtered into dialysis machines, and waste products are removed from it. This purified blood further enters into circulation. Dialysis works on behalf of the kidney. Dialysis can be done three times a week. Two catheters are inserted into the connection. One for receiving the blood, and the other one is for returning the blood into the vein.

5) Do Not Overuse NSAIDs:

Non-steroidal anti-inflammatory drugs (NSAIDs) should not be taken too often because anything more than recommended dose is harmful, especially if you have kidney disease. Please talk to your doctor to determine the right treatment plan for pain and inflammation.

6) Herbal Supplements:

Traditional Chinese medicine from the plant, Red sage, or Salvia miltiorrhiza, plays a major role in the treatment of kidney diseases. It is said that this plant provides protection against renal failure and strengthens the kidneys for a better process of creatinine.

7) Caution With Diuretics:

Diuretics help the body to remove excess fluid and reduce swelling due to fluid retention. But diuretics increase the creatinine levels in kidney diseased patients. So consult a doctor before taking diuretics.

8) Good Sleep:

While sleeping, the creatinine levels in the body decrease.

9) Avoid Smoking:

Cigarette smoking increases the risk of chronic kidney disease and is also harmful to the body in many ways.

So avoid smoking, and it is the best way to reduce kidney disease and creatinine levels.

10) Chitosan Supplements:

This ingredient helps with weight loss and cholesterol.

It is said that chitosan helped with kidney failure by reducing creatinine levels in rats. But always ask a doctor before using chitosan or any other supplement.

11) Avoid the Consumption of Alcohol:

Alcohol consumption affects the liver as well as kidneys too. Excessive alcohol consumption has the potential to,

Conclusion:

High creatinine levels indicate serious medical conditions and create kidney problems. It would be best if you visit a doctor to get the best course of treatment for kidney diseases. In addition, follow proper lifestyle changes and seek a doctor to undergo proper treatment and dialysis to flush out the toxins and waste products from the kidneys.

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Frequently Asked Questions


1.

What is the function of creatinine in the body?

Creatinine is the waste product that is produced by the breakdown of creatine, which is naturally found in the muscles. Creatinine enters the blood by muscle metabolism, which is then absorbed by the kidneys and excreted out of the body.

2.

What is the normal creatinine level?

The normal range of creatinine is:
For men - 0.7 to 1.2 mg/dL.
For women - 0.5 to 1.0 mg/dL.

3.

What is considered a bad creatinine level?

Creatinine levels above the normal range are considered to be bad, as they indicate impairment in kidney function or kidney failure.

4.

What are the symptoms of low creatinine in the body?

Some of the symptoms of low creatinine levels in the body are difficulty exercising because of lack of strength, frail body, pain in the upper-right side of the stomach and jaundice due to inflammation of the liver, tar-colored stools, unintentional weight loss, muscular weakness, muscular pain or stiffness, and dizziness.

5.

What are the symptoms of high creatinine in the body?

The symptoms that result from high levels of creatinine in the blood are swelling (edema), shortness of breath, nausea, vomiting, dehydration, chest pains, tiredness, hypertension, and confusion.

6.

How to reduce creatinine in the body?

The levels of creatinine can be reduced by:
- Reducing protein intake but restricting the consumption of red meat, dairy
- Products, and beans. Consuming more of fruits, vegetables, and whole
- Grains which are rich in fiber.
- Drinking more water to avoid dehydration.
Taking Chitosan supplements.

7.

What causes high creatinine levels?

Creatinine levels increase for patients suffering from chronic kidney disease, kidney obstruction or dehydration, or by consuming too much of food rich in protein, after rigorous exercise, and taking certain medications like antibiotics (Trimethoprim) and H2 blockers (Cimetidine).

8.

What causes low creatinine levels?

The creatinine levels are lower than normal in people with low muscle mass, malnutrition, muscular dystrophy, myasthenia gravis, pregnancy, and sudden weight loss.

9.

What level of creatinine requires dialysis?

The decision to put a patient on dialysis depends on the level of kidney function and the symptoms experienced by the patient. The need for dialysis is made when the estimated glomerular filtration rate (eGFR) is between 5 and 10. eGFR helps the doctor know the level of kidney function and the stage of kidney disease.

10.

Are creatine and creatinine same?

- Creatine and creatinine are both proteins found in our body. The body produces creatine from the amino acids glycine and arginine. It is found in our muscles and it produces energy during high-intensity exercise.
- Creatinine is the waste product that is formed by the metabolism of creatine found in the muscles. This creatinine is taken up by the kidneys and excreted in the urine.

Last reviewed at:
14 Jun 2021  -  7 min read

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