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I have dark patches on my mouth, knuckles, and knees. Why?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 28-year-old female with a dusky skin tone. I have noticed dark patches around my mouth, neck, knuckles, and knees, which cause uneven skin tone. My weight is 139 pounds, and my height is 5.3 feet. I would like to understand the cause and the treatment options for this condition.

Kindly help.

Answered by Dr. Misha Saghir

Education:

MBBS

Professional Bio:

Dr. Misha Saghir is a dedicated dermatologist with expertise in diagnosing and managing a wide range of skin, hair, nail, and cosmetic concerns. Her areas of expertise include acne, pigmentation, eczema, psoriasis, vitiligo, melasma, skin infections, and other hair and nail disorders. With previous experience as a general practitioner in government healthcare, Dr. Misha Saghir combines strong clinical knowledge with a patient-centered approach. She provides evidence-based online consultations, practical treatment plans, clear guidance, and appropriate follow-up care to help patients achieve healthy skin, hair, and nails.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I understand your concern.

Based on your given description, you are most likely having acanthosis nigricans or just hyperpigmentation, which is common on sun-exposed sites or areas that rub most often. In either case, the treatment for pigmentation is the same. For acanthosis, please get your haemoglobin A1C (HbA1c) blood test done, as it is linked to early diabetes and obesity.

Your weight according to height is not much, but I would now suggest shedding a few pounds. The ideal weight is between 55 to 60 for you. Regarding treatment options, there are topical and laser options for this issue.

I am giving you topical management.

  • For body pigmentation, use Glycolic acid 10% cream mixed with Magnesium ascorbyl phosphate 5% cream in equal parts and apply at bedtime on affected areas.

  • For the face, use Azelaic acid 10% cream under the cover of a moisturiser on alternate nights. Avoid Glycolic acid on the face, as it is too strong for the face.

Also, use sunblock with a sun protection factor (SPF) 50 in the morning on the body to avoid further pigmentation. Do this for one month, and you will notice improvement.

If you opt for laser treatment, consider a carbon dioxide (CO2) laser for pigmentation, which typically requires monthly sessions. With this type of laser, you can expect to see results in two to four sessions, depending on the laser available in your area.

I hope you are satisfied with my answer. For further queries, you can consult me at iCliniq.

Thank you.

Medically reviewed by iCliniq medical review team
Published At March 1, 2026
Reviewed At March 3, 2026

Education:

MBBS

Professional Bio:

Dr. Misha Saghir is a dedicated dermatologist with expertise in diagnosing and managing a wide range of skin, hair, nail, and cosmetic concerns. Her areas of expertise include acne, pigmentation, eczema, psoriasis, vitiligo, melasma, skin infections, and other hair and nail disorders. With previous experience as a general practitioner in government healthcare, Dr. Misha Saghir combines strong clinical knowledge with a patient-centered approach. She provides evidence-based online consultations, practical treatment plans, clear guidance, and appropriate follow-up care to help patients achieve healthy skin, hair, and nails.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

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Companion

Dark Patches on Skin Companion

How it works

Dark patches on your skin, especially around areas like your mouth, neck, knuckles, and knees, can be a common concern. This companion helps you understand potential causes and treatment approaches.

1

Skin
Patches

2

Health
Link

3

Weight
Management

4

Topical
Treatments

5

Sun
Protection

6

Laser
Options

This information is based on general medical guidance. It is not a substitute for professional medical advice; consult a qualified clinician.

Always consult a doctor before taking medication; self-medication carries serious health risks. Take exact prescribed doses, and never start, change, or stop treatment without medical supervision.

Education:

MBBS

Professional Bio:

Dr. Misha Saghir is a dedicated dermatologist with expertise in diagnosing and managing a wide range of skin, hair, nail, and cosmetic concerns. Her areas of expertise include acne, pigmentation, eczema, psoriasis, vitiligo, melasma, skin infections, and other hair and nail disorders. With previous experience as a general practitioner in government healthcare, Dr. Misha Saghir combines strong clinical knowledge with a patient-centered approach. She provides evidence-based online consultations, practical treatment plans, clear guidance, and appropriate follow-up care to help patients achieve healthy skin, hair, and nails.

This doctor is not available for online consultations on the platform anymore.

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