Published on Oct 30, 2016 and last reviewed on Jan 11, 2019 - 2 min read
Here in this article, I have discussed the causes and management of dirty non-cleanable darkness over the neck and underarms, which is known as Acanthosis nigricans.
Acanthosis nigricans is characterized by the occurrence of velvety brownish skin mainly involving intertriginous areas, or body folds like the neck, axilla, anogenital, and groin areas. In this condition, it should be noted that the pigmentation is not due to increased melanin (pigments synthesized by melanocytes), but because of hyperkeratosis, that means due to abnormal thickening of the outermost layer of the skin.
It may be related to obesity, heredity, diabetes, drug-induced such as Nicotinic acid, OCPs - oral contraceptive pills, and corticosteroids or may be a cutaneous manifestation of some internal malignancy such as adenocarcinoma of the gastrointestinal tract or genitourinary tract or lymphoma.
Acanthosis nigricans starts as pigmentation, dryness, and roughness of the skin with small palpable thickened grain like elevation which gives it a velvety texture.
Types of Acanthosis Nigricans:
Broadly, it can be divided into two types:
In benign form, skin lesions may be present at birth but usually, develop during childhood or puberty. They may be less severe, involve one side of the body, progress very slowly when compared to malignant one.
The lesions are more severe and more extensive. Pigmentation is more prominent and is not confined to thickening of the outermost layer of the skin in skin folds only, but also involves palms, nails, and hair. Irritation is common. The mucous membranes and mucocutaneous junctions are involved in 50 percent of cases, and warty thickening around the lips and eyes are the most common presenting symptoms. Removal of the tumor may be associated with regression of the clinical sign.
To know more about Acanthosis nigricans, consult an acanthosis nigricans specialist online --> https://www.icliniq.com/ask-a-doctor-online/dermatologist/acanthosis-nigricans
Query: Hello doctor, I had undergone a Co2 laser treatment around my eyes about three and half years ago. Now, I am left with dark circles under the eyes along with hyperpigmentation and redness. About one and half weeks back, the doctor prescribed me a cream that has Kojic acid 1%, Glycolic acid 5%, Beta... Read Full >>
Answer: Hi, Welcome to icliniq.com. I have gone through your query and reviewed the pictures (attachment removed to protect patient identity). I suggest you a moderately potent topical steroid like Fluticasone propionate 0.05% cream, twice daily for a few days. Consult your specialist doctor, discuss with h... Read Full
Query: Hi doctor, I am a 27 year old female. I am getting acne since the age of 13. I have asthma. No product has worked on my face. I have sensitive oily skin. Kindly advice some solution. Read Full >>
Answer: Hello, Welcome to icliniq.com. I have read your query and I understand your concern. Acne has several grades depending on the type of lesions. In grade 1, I prefer to advise topical Clindamycin in the morning and Benzoyl peroxide alternatively with topical retinoids in the night-time. Oral antibioti... Read Full
Article Overview: Environmental factors, lifestyle preferences, and cultural environment play major roles in the increasing prevalence of childhood obesity worldwide. By following the guidelines on the basis of ayurvedic fundamentals, parents can effectively manage their child's obesity. Read Article
A child is considered obese when his/her Body Mass Index (BMI), a measurement obtained by dividing a person's weight by the square of the person's height, exceeds 30 Kg/m2. In ayurveda, obesity has been elaborately described by using the term atisthaulya. Childhood obesity ... Read Article
Do you have a question on Obesity or Hyperpigmentation?Ask a Doctor Online