Q. Kindly explain about ACD-A.

Answered by
Dr. Sumit Chawla
and medically reviewed by iCliniq medical review team.

Hello doctor,

Not a symptom, but a curious educational question about ACD-A. There are companies that decide to show in big bold letters that their ACD-A is not for direct intravenous infusion, while others do not list this in their descriptions. Other companies state that their product is for research purposes only. These are a kind of strange to me as the FDA considers ACD-A to be a safe chemical for even doctors to use. Another strange thing is how some companies state that their product should be stored between 2 to 8 °C while another company states between 15 °C (59 °F) and 30 °C (86 °F). Are these variations considered meaningless? Or is there something behind these variations that could cause a danger to people who need to buy the right ACD-A (anticoagulant citrate dextrose solution)?

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Dr. Sumit Chawla

MBBS., MS ORTHO
Orthopedics And Traumatology

Hi,

Welcome to icliniq.com.

  • The same product by different companies differs not only in their physical properties, but their biochemical profile as well.
  • They should be stored and used as per their description; otherwise it affects the quality of the drug. It can make the product grossly harmful for use or decrease its effectiveness.
  • When some drug companies try to get license for manufacturing a known product they make some changes in the preparation methodology or composition to render their product more physical stability or early action or delayed activity.
  • For manufacturing this product they have to go through one of the phase of clinical trials where the last part involves use in a general population rather than small volunteer groups.

For further clarifications consult a general practitioner online -->https://www.icliniq.com/ask-a-doctor-online/general-practitioner

Hello doctor,

Are all ACD-A products the same and not for direct intravenous infusion? Why do some companies mention in their description that their ACD-A is for research purposes only?

Dr. Sumit Chawla

MBBS., MS ORTHO
Orthopedics And Traumatology

Hi,

Welcome back to icliniq.com.

  • FDA (Food and Drug administration) describes research purpose only products as devices in the laboratory phase of development.
  • These products also may be offered and promoted for non-clinical purposes, such as basic research activities.
  • All ACD-A (anticoagulant citrate dextrose solution) are not the same and cannot be given by direct IV (intravenous) route unless specified by manufacturer.

For further information consult a general practitioner online --> https://www.icliniq.com/ask-a-doctor-online/general-practitioner

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