Dr. Sumit Chawla
Orthopedician and Traumatology
The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.
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Patient's Query
Hello doctor,
Not a symptom, but a curious educational question about ACD-A. There are companies that decide to show in big bold letters that their ACD-A is not for direct intravenous infusion, while others do not list this in their descriptions. Other companies state that their product is for research purposes only. These are a kind of strange to me as the FDA considers ACD-A to be a safe chemical for even doctors to use. Another strange thing is how some companies state that their product should be stored between 35.6 degree Fahrenheit to 46.4 degree Fahrenheitwhile another company states between 59 °F and (86 °F). Are these variations considered meaningless? Or is there something behind these variations that could cause a danger to people who need to buy the right ACD-A (anticoagulant citrate dextrose solution)?
Hi,
Welcome to icliniq.com.
The same product by different companies differs not only in their physical properties, but their biochemical profile as well. They should be stored and used as per their description; otherwise it affects the quality of the drug. It can make the product grossly harmful for use or decrease its effectiveness. When some drug companies try to get license for manufacturing a known product they make some changes in the preparation methodology or composition to render their product more physical stability or early action or delayed activity. For manufacturing this product they have to go through one of the phase of clinical trials where the last part involves use in a general population rather than small volunteer groups. Thank you.
Patient's Query
Hello doctor,
Are all ACD-A products the same and not for direct intravenous infusion? Why do some companies mention in their description that their ACD-A is for research purposes only?
Hi,
Welcome back to icliniq.com.
FDA (Food and Drug administration) describes research purpose only products as devices in the laboratory phase of development. These products also may be offered and promoted for non-clinical purposes, such as basic research activities. All ACD-A (anticoagulant citrate dextrose solution) are not the same and cannot be given by direct IV (intravenous) route unless specified by manufacturer. Thank you.
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Orthopedician and Traumatology
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