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Could infant rash be linked to an immune reaction?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My 14-month-old daughter has flare-up rashes. The rashes started last, and she still has them at the moment. She does not show any other symptoms and still seems well, but the rash is quite severe. We have tried to eliminate nappies, milk, washing powder, etc. However, it does not seem to be making any difference. Could you advise on anything we could do?

Please help.

Answered by Dr. Dhepe Snehal Madhav

Hi,

Welcome to icliniq.com.

The differential diagnosis is irritant contact dermatitis and urticarial rash. Apply Desonide cream at night for ten days. Also, apply Calamine lotion thrice daily for ten days.

  1. Do you have any history of fever?
  2. Is it widespread or localized to the diaper area?
  3. Do you have any history of atopy?
  4. Did you experience a similar episode in the past?

I hope this answers your query.

Please let me know if I can assist you further.

Thank you.

Patient's Query

Hi doctor,

Thank you for your response.

Do you know what might be causing this?

Answered by Dr. Dhepe Snehal Madhav

Hi,

Welcome back to icliniq.com.

It is atopic dermatitis, a widespread allergic response in babies or infants to allergens or irritants. The cause can be external stimuli, ammonia in urine (diaper contact dermatitis), or dietary protein. I suggest using Desonide cream at night for ten days. Avoid cow milk or related formula milk, egg, and groundnuts. Frequently change diapers. Take care of the skin by washing it in gentle lukewarm water.

  1. Do your parents have a history of atopy?
  2. Does the flare-up of atopic dermatitis occur with a change in weather?
  3. Is there any seasonal aggravation?
  4. Did you use strong soaps?
  5. Did you use any new cosmetic products like powder, cream, or scented fragrance lotion?
  6. Is she allergic to woolen clothes, dust, or pets in the house?
  7. Does she have any history of drug allergy to Amoxicillin or any other drug?
  8. Does she have any history of fever?
  9. Is the rash localized to the diaper area or widespread?

I hope this answers your query.

Please let me know if I can assist you further.

Thank you.

Patient's Query

Hi doctor,

No, there is no fever, but she does have diarrhea. It is widespread, but it does seem to be more severe in the diaper area. It is on the cheeks, arms, and legs. There is no history of it in her or the family, and it never happened before.

  1. Could it possibly be a virus? The anti-allergy medicine takes it away more or less straight away.
  2. Would it do this if it were a rash caused by a virus? She always drinks cow's milk.

Kindly assist.

Answered by Dr. Dhepe Snehal Madhav

Hi,

Welcome back to icliniq.com.

Three to four times the frequency of semi-solid to solid stools is normal. Stop any new food that you have started giving her recently. Maintain proper hygiene of bed linen and clothes. Stay away from pets, if any. Diarrhea with the rash can be a viral infection (rotavirus).

Please answer these questions.

  1. Are there any pets at home?
  2. What is the frequency of stools?
  3. Do the symptoms of diarrhea and rash start at the same time?
  4. Is there excessive, unreasonable crying of the baby?

I hope this answers your query.

Please let me know if I can assist you further.

Thank you.

Patient's Query

Hi doctor,

Thanks for the reply.

No, we do not have any pets. It seems to flare up when the baby is asleep in her cot or the pram. When she wakes up from sleep, the rash returns. We have washed all her clothes and bed linen on a 60-degree wash with no washing powder. Cut all dairy from her diet. She is doing one stool per day, but it is not like her normal stools. She still seems fine in herself and has no temperature.

What do you think it could be?

Kindly assist.

Answered by Dr. Dhepe Snehal Madhav

Hi,

Welcome back to icliniq.com.

It is atopic dermatitis (allergic rash) due to an extrinsic allergen. Clean the pram and baby linens or clothes regularly. An anti-allergic drug will suffice.

I hope this helps.

Answered byDr. Dhepe Snehal Madhav

Medically reviewed byDr. Preetha. J

Published At October 20, 2020
Reviewed AtOctober 27, 2025

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Dhepe Snehal Madhav
Dr. Dhepe Snehal Madhav

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