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What pathophysiology do you observe in breast cancer?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

What are the physical findings seen in breast cancer? Please explain the pathophysiology observed in breast cancer.

Thank you.

Hi,

Welcome to icliniq.com.

These are the physical findings of breast cancer.

  • There can be a painless lump or a change in breast size, skin changes, nipple inversion, nipple abnormalities or discharge, and an axillary lump.
  • The pathophysiology shows damage to DNA, and genetic changes lead to breast cancer.
  • It is also linked to other factors such as estrogen exposure, smoking, age, and family history.
  • Some individuals inherit defects in BRCA1, BRCA2, PTEN (phosphatase and tensin homolog), and P53 (tumor protein).
  • People having a family history of ovarian or breast cancer can have an increased risk of getting breast cancer.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.

Medically reviewed byiCliniq medical review team

Published At September 28, 2017
Reviewed AtDecember 22, 2025

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