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What pathophysiology do you observe in breast cancer?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

What are the physical findings seen in breast cancer? Please explain the pathophysiology observed in breast cancer.

Thank you.

Answered by Dr. Shravana Kumar Chinnikatti

Education:

MBBS

Professional Bio:

Dr. Shravana Kumar Chinnikatti is a Radiation Oncologist, Radiotherapist, and Medical Oncologist. His treatment plans commonly include radioactive implantations, external beam radiotherapy, hyperthermia, and combined modality therapy. He completed his MBBS from Kasturba Medical College in 2000 and MD from MS Ramaiah Medical College in 2005. He is currently practicing in Bangalore with 23 years of clinical experience.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

These are the physical findings of breast cancer.

  • There can be a painless lump or a change in breast size, skin changes, nipple inversion, nipple abnormalities or discharge, and an axillary lump.
  • The pathophysiology shows damage to DNA, and genetic changes lead to breast cancer.
  • It is also linked to other factors such as estrogen exposure, smoking, age, and family history.
  • Some individuals inherit defects in BRCA1, BRCA2, PTEN (phosphatase and tensin homolog), and P53 (tumor protein).
  • People having a family history of ovarian or breast cancer can have an increased risk of getting breast cancer.

I hope this helps.

Kindly follow up if you have more concerns.

Thank you.

Medically reviewed by iCliniq medical review team
Published At September 28, 2017
Reviewed At December 22, 2025

Education:

MBBS

Professional Bio:

Dr. Shravana Kumar Chinnikatti is a Radiation Oncologist, Radiotherapist, and Medical Oncologist. His treatment plans commonly include radioactive implantations, external beam radiotherapy, hyperthermia, and combined modality therapy. He completed his MBBS from Kasturba Medical College in 2000 and MD from MS Ramaiah Medical College in 2005. He is currently practicing in Bangalore with 23 years of clinical experience.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Shravana Kumar Chinnikatti is a Radiation Oncologist, Radiotherapist, and Medical Oncologist. His treatment plans commonly include radioactive implantations, external beam radiotherapy, hyperthermia, and combined modality therapy. He completed his MBBS from Kasturba Medical College in 2000 and MD from MS Ramaiah Medical College in 2005. He is currently practicing in Bangalore with 23 years of clinical experience.

This doctor is not available for online consultations on the platform anymore.

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