Get Comprehensive Medical Second Opinion.

iCliniq / Answers / Obstetrics and Gynaecology / Down's Syndrome / Do my wife's NT scan and double marker test results show a high risk for Down's syndrome?

Q. Do my wife's NT scan and double marker test results show a high risk for Down's syndrome?

Answered by
Dr. Deepti Verma
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jul 24, 2017 and last reviewed on: Oct 09, 2018

Hi doctor,

My wife had NT scan and double marker test at 12 weeks and 3 days of pregnancy. The report is as follows, CRL is 59.2 mm, NT is 1.45 mm, free beta-hCG is 84.84 IU/L, equivalent to 2.217 MoM and PAPP-A 0.712 IU/L equivalent to 0.282 MoM. Trisomy 21 is 1: 450 1:47 and trisomy 18 is 1: 5315. I wanted to know about if the risk in the first-trimester screening window is positive.

#

Hi,

Welcome to icliniq.com.

I have read your question and understand the concerns.

  • The report is showing a high risk for trisomy 21 or Down's syndrome. This first-trimester screening is 95 % sensitive, hence, if the risk is positive, then the amniocentesis should be done to confirm the fetal karyotype.
  • Down's syndrome should definitely be ruled out by amniocentesis before continuing the pregnancy.

Hope you found the answer helpful. Regards.

For more information consult an obstetrician and gynaecologist online --> https://icliniq.com./ask-a-doctor-online/obstetrician-and-gynaecologist

Hi doctor,

Thanks for your reply. That means there is a high risk of the baby having Down's syndrome. What are the consequences?

#

Hi,

Welcome back to icliniq.com.

  • Yes, there is a high risk of Down's syndrome. A baby with Down's syndrome has mental retardation, growth restriction, and has congenital anomalies in various organs.
  • Therefore, it is always advisable to diagnose it prenatally by amniocentesis and termination of pregnancy, if the karyotype shows Down's syndrome.

For more information consult an obstetrician and gynaecologist online --> https://icliniq.com./ask-a-doctor-online/obstetrician-and-gynaecologist

Was this answer helpful?

 | 
 

This is a sponsored Ad. icliniq or icliniq doctors do not endorse the content in the Ad.

Also Read Answers From:

Comprehensive Medical Second Opinion.Submit your Case

✶

Related Questions & Answers


What is the significance of minimal fluid in POD?

Query: Hi doctor, We had unprotected sex and after that she took I-pill within one hour. Is there any chance of pregnancy? She had an ultrasound and there is minimal fluid found in POD. Otherwise, everything is fine. Please suggest what to do now.  Read Full »

What does amniocentesis mean?

Query: Hi doctor, My wife is 27 years old and 13 weeks pregnant now. As per suggestion from doctor, we went for a double marker test. It is found that trisomy 21 + NT risk is 1:86 and doctor suggested for amniocentesis procedure. Now I am confused and do not know what to do. My wife scared that the proce...  Read Full »

My second anomaly scan shows two markers for DS. Is there a need to worry?

Query: Hello doctor, I am a 31 year old female. My first trimester NT and double marker test showed a very low risk of 1:3690 for DS and 1:100000 for two other abnormalities. During the second-trimester anomaly scan, the doctor found two markers, CP cyst and mild RPD 4 mm and 4.5 mm. I have given blood fo...  Read Full »

Also Read

COVID-19 Vaccines
A COVID-19 vaccine provides acquired immunity against the new Coronavirus. Read the article to know everything about the...  Read more»
Does CD marker help in identification of blood cancer?
Hi doctor, I am a 25-year-old male suffering from joint pain and pain in the knees. I also have nausea, vomiting, gynec...  Read more»
I suddenly got fainted and woked up with bruising in eyes. Why?
Hi doctor,I am 28 years old with normal weight and following a vegetarian diet. Last month, I fainted at home and my fri...  Read more»

Ask your health query to a doctor online?

Ask an Obstetrician & Gynaecologist Now

* guaranteed answer within 4 hours.

Disclaimer: All health Q&As published on this website are not intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek the advice from your physician or other qualified health-care providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.