Elevated Igm

Elevated IgM indicates various conditions such as macroglobulinemia, early viral hepatitis, rheumatoid arthritis, kidney disease, or the presence of a parasitic infection. When the body produces high IgM blood becomes thicker and shows symptoms like weakness, loss of appetite, fever, weight loss, and neuropathy.

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I have elevated IgM and elevated kappa light chains. What does it indicate?

Query: Hi doctor, I am a 34 year old male. My free kappa light chains are elevated, but the ratio came back normal. IgM is also elevated, but IgG and IgA are normal. What does this mean? I do have a history of DVT. I am on blood thinners. I also did angiograms of my lower extremities. Can you help me under...  Read Full »


Dr. Shravana Kumar Chinnikatti

Answer: Hi, Welcome to icliniq.com.I have seen the reports (attachment removed to protect patient identity). IgM and kappa can be raised in any acute infection. Mixed infection probably started with viral and superadded bacterial infection. Repeat all blood tests after three months for evaluation. Start on ...  Read Full »

What are the chances of reinfection in infectious mononucleosis?

Query: Hello doctor, I am a 20-year-old male with no previous major health issues. I currently weigh around 165 lbs with a height of 6 feet. Before three months, I was diagnosed with infectious mononucleosis, and I was cured, or I thought so. Since then, I have dealt heavily with weakness and pain in my a...  Read Full »


Dr. Utkarsh Sharma

Answer: Hello, Welcome to icliniq.com I understand your concern and will help you regarding it. In general, if you have had infectious mononucleosis (IM) in the past, then the chances of reinfection are very slim. However, the feeling of tiredness may last for few months. Also, in susceptible...  Read Full »

Is it something dangerous if you see isolated IgM levels elevated?

Query: Hi doctor, I am 29 years old. I have a problem and I need someone to help me. I am going to do an elective surgery and I have done a medical checkup. All the blood tests came back normal. I also did tests for IgG and IgM. IgG came back normal but IgM was elevated with a level of 8.41 g/L. My health...  Read Full »


Dr. Sugreev Singh

Answer: Hi, Welcome to icliniq.com. Your IgM (immunoglobulin M) is high but it is not severe. You do not have symptoms and so there is nothing to worry about it. It is not dangerous and IgM is seen during infections. It shows that your body has an infection now and antibodies in the body deal with it. Nor...  Read Full »

What does elevated M protein mean?

Query: Hello doctor,I am wondering about my lab work due to M protein in my blood. I have my lab work available, and I have some questions since I have not been able to get to my doctor.  Read Full »


Dr. Sugreev Singh

Answer: Hi, Welcome to icliniq.com. I have gone through your reports (attachment removed to protect patient identity). There were few changes seen like vitamin insufficiency, increased ALT (alanine transaminase), and AST (aspartate transaminase), indicating liver infection or inflammation. Apart from this...  Read Full »

What causes extreme fatigue?

Query: Hi doctor, I am a 31 year old male. I am managing an IT company. I have suffered from periods of extreme fatigue for the past one and a half year. The first period of fatigue was one and a half year back and it lasted for around 18 days. Then I felt fine for the next five months. From then till tod...  Read Full »


Dr. K. V. Anand

Answer: Hi, Welcome to icliniq.com. You pointed that you never had the period of fatigue problem before. Can you try to recall what happened during that period (before one and a half years)? Was there any excess stress situation or anxiety problems? As you are healthy and doing physical exercise, i...  Read Full »

Epstein-Barr IgM is positive, but undetectable in PCR. Still, I am sick, could it be chronic fatigue?

Query: Hi doctor, I have had reactivated Epstein-Barr for a year. I recently got a blood test, which said, faint monoclonal band detected in the gamma region, repeat blood test in six months. There is no immunoparesis, and my levels have risen in the last four months, but still in the normal range. What d...  Read Full »


Dr. Shinas Hussain. A. P

Answer: Hello, Welcome to icliniq.com. I have gone through your query, and I can understand your concerns. The brief history you have described suggest a possibility of past infection with EBV (Ebstein-Barr virus). Probably you had an episode of IMN( infectious mononucleosis) in the childhood, which is quit...  Read Full »

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