HomeAnswersRheumatologylymphadenopathy

Can an enlarged lymph node at the side of my neck be due to autoimmune disease?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have enlarged lymph nodes on the side of my neck and experienced a low fever on and off for four days. I tested positive for ANA (Antinuclear antibody) 1:16, speckled pattern. No sign of abnormality in my chest X-ray result. I do not have any other symptoms, such as skin rash or muscle pain. Do I have an autoimmune disease? What might it be?

Please answer.
Answered by Dr. Sugreev Singh

Education:

MD

Professional Bio:

Dr. Sugreev Singh is an experienced General Surgeon with expertise in Internal Medicine and General Medicine. He is skilled in performing a wide range of surgical procedures and managing complex medical conditions with a holistic approach. Known for his clinical precision and compassionate care, Dr. Singh is dedicated to delivering effective, patient-centered treatment to promote long-term health and recovery.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Hi,

Welcome to icliniq.com.

Thank you for writing, and I understand your concern.

When actually in large lymph nodes, it can be due to infection. Bacterial infection can lead to such swollen lymph nodes.

But at the same time, positive ANA (Antinuclear antibody) indicates for them, so there might be rheumatoid arthritis or lupus. When you do not have any symptoms of these diseases, do not worry.

Even healthy people show ANA positive, so there is no treatment required if you do not have symptoms. For enlarged lymph nodes, antibiotics can be given, and they will shrink most probably.

Please send me a picture of enlarged lymph nodes and your reports.

Are you allergic to any antibiotics?

Do you have any difficulties in swallowing?

Please answer.

The Probable causes

Infection.

Investigations to be done

USG (ultrasonography) of the neck.

Differential diagnosis

Cyst.

Probable diagnosis

Enlarged lymph node.

Treatment plan

Antibiotics.
Medically reviewed by Dr. Preetha. J
Published At October 31, 2021
Reviewed At August 25, 2025

Education:

MD

Professional Bio:

Dr. Sugreev Singh is an experienced General Surgeon with expertise in Internal Medicine and General Medicine. He is skilled in performing a wide range of surgical procedures and managing complex medical conditions with a holistic approach. Known for his clinical precision and compassionate care, Dr. Singh is dedicated to delivering effective, patient-centered treatment to promote long-term health and recovery.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. Preetha J. is a proficient Dental Surgeon with expertise in cosmetic dentistry, restorative procedures, root canal treatments, and oral surgery. She is known for her gentle approach, precision, and commitment to patient comfort. Dr. Preetha combines advanced dental techniques with personalized care to ensure optimal oral health and aesthetic results, helping patients achieve confident, healthy smiles. Currently, she contributes her expertise as a valuable member of the medical reviewer team at iCliniq.com. 

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Sugreev Singh
Dr. Sugreev Singh

Internal Medicine

Education:

MD

Professional Bio:

Dr. Sugreev Singh is an experienced General Surgeon with expertise in Internal Medicine and General Medicine. He is skilled in performing a wide range of surgical procedures and managing complex medical conditions with a holistic approach. Known for his clinical precision and compassionate care, Dr. Singh is dedicated to delivering effective, patient-centered treatment to promote long-term health and recovery.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
Listen to related tracks in our music library

Related Questions

Can an enlarged lymph node at the side of my neck be due to autoimmune disease?

Testicular Seminoma - Causes, Symptoms, Diagnosis, and Treatment

Bacterial Infections of Lip

Bacterial Infections of the Colon - Types and Treatment

Does many enlarged lymph nodes with EBV indicate lymphoma?

Testosterone Gel - Uses, Mechanism of Action, Precautions and Side Effects

Comprehensive Second Opinion

Read answers about:

rheumatoid arthritislymphadenopathy

Ask your health query to a doctor online

Rheumatology

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.