Q. Can lymph node enlargement in mouth, legs and neck mean lymphoma?

Answered by
Dr. Prakash H. Muddegowda
and medically reviewed by Dr. Divya Banu M
This is a premium question & answer published on Sep 11, 2019 and last reviewed on: Sep 14, 2019

Hello doctor,

I was in a car accident four years back. After one week while I was having bath, I felt one small lymph node in my left neck. I did not feel it before. It was little bigger that time. By the time it is getting smaller but not going to its original size. I cannot see it now but I can feel it. So, I am worried and popping it all the time. Recently, I found one gland in floor of the mouth in left side and it is very small and not growing in size. Sometimes I feel swelling in left side of mouth and left leg. I got no night sweat, no fever and no weight loss at all. I got five small petechiae (red blood spots) in right chest. I have attached my complete blood test history for three months.


Constant left shoulder pain, bone pain, hand pain. extreme fatigue, and tiredness. I feel something struck in throat. Bowel habit change.


Doxycycline Hyclate 100 mg for two weeks. Amoxycillin 500 mg for one week.

My questions to you are as follows:

1. Do I have lymphoma or leukemia?

2. If your answer of no. 1. is no, then why the lymph nodes are not going back to their original size after completing whole antibiotic dosage?

3. Why my WBC and lymph % are fluctuating too much?

4. Can lymphoma be ruled out from CBC test?

5. What is your opinion about my blood report?



Welcome to

Based on your query, my opinion is as follows:

No, it is neither lymphoma nor leukemia. There is no cell predominance (either neutrophil or lymphocyte or any immature cells) or the counts are also not high enough to think of leukemia. Lymphoma lymph nodes are usually multiple and do not regress in size. Lymph nodes usually take longer to regress and sometimes, mild infection in the location could be making it to be active. It could also be chronic lymphadenitis, with variable amount of fibrosis inside it, due to which, it may not regress back to its original size. If it was lymphoma, it would be increasing and multiple sites and multiple nodes together would be enlarged.

WBC are cells related to fighting infections and inflammations. As the body is fighting some infection or other in everything (food, water, air, etc.), it will vary. Also, stress and hormonal variations can affect it too. If the count is not shooting excessively over the normal range, not to worry. No, usually lymphoma cannot be ruled out from CBC test. Fine needle aspiration cytology of lymph node or biopsy of lymph node is essential. However, at present, it will not be essential looking at small lymph nodes.

Blood report, overall is good. Mild neutrophil increase, indicating possible mild infection or stress. Stress could be responsible for all the symptoms at present. Nothing in the blood report, can explain the symptoms you have. Check calcium level once. As the platelet count is normal and you do not have any bleeding, petechiae could be due to small pressure spots. It will disappear. Not to worry about it. If it starts occurring at multiple spots, then prothrombin and activated partial thromboplastin time evaluation may be necessary.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
Can Hashimoto's disease cause enlarged lymph nodes?

The best approach would be to repeat your ultrasound again in a month's time and if it has not resolved, I suggest that you have an FNAC (fine-needle aspiration cytology) done ...   Read full

Will having 130 bpm during exercise increase the risk of stroke in heart patient?

.. your queries, you should visit a cardiologist regularly and avoid strenuous activities in order to reduce the risk of acute coronary syndrome. Your echo has some abnormalities which are age-related and there is no evidence of CAD. However, calcium...   Read full

I have enlarged lymph nodes in my neck from six months. Do I need a biopsy?

In my opinion, you should get a FNAC (fine needle aspiration cytology) done from the lymph nodes to rule out any infection or malignancy ...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Monkeypox Virus - Symptoms, Diagnosis, Treatment, Complications, and Prevention
Monkeypox is a zoonotic viral disease. This virus got its name as it was first noticed in laboratory monkeys in the late...  Read more»
Tomato Fever - Causes, Symptoms, Diagnosis, Treatment, and Prevention
Tomato fever is an unidentified and fast-spreading type of viral infection seen in young children. Scroll down to know m...  Read more»
Histrionic Personality Disorder - Causes, Signs, Symptoms, Diagnosis and Treatment
Histrionic personality disorder causes variations in the thinking ability of a person. Read this article to know more.  Read more»

Ask your health query to a doctor online?

Ask a Hematologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.