How can motor and sensory nerve weakness be managed in an AIDP patient?

Hello,

Welcome to icliniq.com. Acute inflammatory demyelinating polyneuropathy (AIDP) or Guillain barre syndrome (GBS) is an autoimmune disease. Which can be primary or also can be secondary other autoimmune diseases. As you are telling that you are recovering, it is a good thing. There is no medicine for rapid recovery after six months. Only medication available is for stopping the progression of weakness in the acute stage (IV Ig or Plasmapheresis). At this stage, you need regular physiotherapy and it takes a few weeks to a few months for recovery. Few patients do not have a complete recovery. Also, you should get further test for detecting any secondary autoimmune disease antinuclear antibodies (ANA), C-ANCA (antineutrophil cytoplasmic autoantibodies), P-ANCA (perinuclear antineutrophil cytoplasmic antibodies), serum angiotensin converting enzyme (ACE) level. Sometimes, chronic demyelinating neuropathy can present as acute presentation. For that need to see nerve conduction velocity (NCV) graphs and if suspected, may need nerve biopsy. Investigations to be done are 1.NCV all four limbs (to be reviewed). 2.ANA, C-ANCA, P-ANCA, serum ACE levels. 3.Sural nerve biopsy. 4.Cerebrospinal fluid (CSF) examination to look for albuminocytological dissociation. The differential diagnosis are 1.AIDP (acute inflammatory demyelinating polyradiculoneuropathy). 2.Acute presentation of chronic inflammatory demyelinating polyneuropathy (CIDP).