Q. Does HBV core Ab total reactive mean hepatitis B?

Answered by
Dr. Parth R Goswami
and medically reviewed by Dr. Divya Banu M
This is a premium question & answer published on Aug 14, 2019

Hello doctor,

Hepatitis B surface antigen HBsAg HBV is negative. Hepatitis B HBV core Ab total*Q is reactive. Kindly help me. Do I have hepatitis B or am I immune? Do I need any other tests done? I also did liver profile test. ALT 21 U/L, AST 19 U/L, alkaline phosphate 147 U/L written high. I also did the liver elastography which says normal.

Dr. Parth R Goswami

Hematology Pathology


Welcome to icliniq.com.

The patient develops an antibody against core antigen during the fight against hepatitis. However, core antibody development is suggestive of infection by hepatitis B antigen. It is not a marker of immunity.

If you want to rule out whether you are immune or not investigate with anti-HBsAg antibody estimation testing. If you have IgG HbsAag antibody in blood than you are immune to hepatitis B.

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