Are proton pump inhibitors safe for treating Helicobacter pylori infection?

Question

Hi doctor,

I had an endoscopy nine days ago, and the doctor performed the rapid urease test (RUT) for Helicobacter pylori. The result turned pink after 24 hours, and he mentioned it was weakly positive, suggesting no need for antibiotics. I have a doubt; even if it is weakly positive, do I still have H. pylori? If left untreated with antibiotics, could it become stronger over time? I underwent an endoscopy due to a stomach-burning sensation, and the doctor prescribed only Pan 80 for two months to take at night before food. Two years ago, I was diagnosed with fundal gastritis with H. pylori. At that time, the RUT turned pink within 30 minutes. I took an H. pylori kit for 15 days, and now the condition is clear with no fundal gastritis. The current medication includes Pan 80, and in the past, there was a history of taking the HP Kit for 10 days before the endoscopy. I am concerned about whether it might weaken my body, as taking too many proton pump inhibitors (PPIs) can hinder the absorption of minerals. What should I do? Should I take an H. pylori kit, or is it okay to continue with Pan 80? Please help.

Answer 1

Hi,

Welcome to icliniq, and thank you for choosing us as your provider for health care.

I have gone through your history and understand your concerns.

If your doctor has diagnosed weakly positive H. pylori through the RUT (rapid urease test) but suggested no antibiotics, it might indicate a less aggressive or dormant presence of the bacteria. However, the decision to treat an H. pylori infection is based on various factors, including symptoms and the overall health condition of the patient. If you are experiencing burning sensations in your stomach and have concerns about the infection becoming stronger over time, it is reasonable to discuss your worries with your doctor. You can inquire about the possibility of further evaluation or alternate treatment options. Long-term use of proton pump inhibitors (PPIs) like Pan 80 (Pantoprazole) might impact mineral absorption and could have other effects on your body. Your doctor likely prescribed it to reduce stomach acid and alleviate symptoms.

I hope this helps you. If you have further questions or need additional guidance, feel free to contact me.

Thank you.