Proton-pump Inhibitors

Proton pump inhibitors (PPIs) are drugs that are used to reduce the amount of acid produced by the stomach lining. They are used in the treatment of heartburn or gastroesophageal reflux disease (GERD), gastric ulcers, and to prevent damage to the lower esophagus. Omeprazole, Lansoprazole, Rabeprazole, and Pantoprazole are some of the commonly used drugs of this group.

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How can I treat the pain a little left under my Adam's apple?

Query: Hello doctor, There is pain under Adam's apple a little to the left. I have a history of acid reflux. There is a pain in the throat with acid reflux. I did see an ENT about two years ago. Everything was fine except for swollen vocal cords due to the acid reflux. I also had thyroid studies and blood ...  Read Full »


Dr. Manu Wilfred

Answer: Hello, Welcome to icliniq.com. Gastroesophageal reflux disease typically presents with heartburn and regurgitation. Extraesophageal symptoms include a sore throat, hoarse voice, feeling of food stuck in the throat, chest pain etc. Upon examination of the throat, the finding of swollen vocal cords ...  Read Full »

What can cause bloating, irregular bowel and watery stool?

Query: Hi doctor, I am suffering from irregular bowel. I feel burning sensation in the stomach and anus. If I eat anything spicy, I need to go to restroom immediately. My poop smells and is semisolid, sometimes watery but not like diarrhea. I am suffering with this condition for past one year. I am tak...  Read Full »


Dr. Anshul Varshney

Answer: Hi, Welcome to icliniq.com. You are suffering from a condition known as irritable bowel syndrome (IBS). Your history is a classical suggestive of that. However, IBS is a diagnosis of exclusion. So, we need to be sure it is not anything else like ulcerative colitis, thyroid disorder or autonom...  Read Full »

Blood in vomit after drinking too much alcohol. Kindly help.

Query: Hello doctor,I am a 20 year old male. About three days ago, I vomited bright red blood after consuming excessive alcohol. This is the first time I have consumed more than one beer and I was also unconscious. I have not been having any pains or any other symptoms. After the first vomit of blood, I pu...  Read Full »


Dr. Ashaq Hussain Parrey

Answer: Hello, Welcome to icliniq.com. I went through your post. At this age, bleeding with vomiting is likely due to an injury to the lower esophagus because of the force of the vomit. If the bleeding was severe, then an upper GI (gastrointestinal) endoscopy is necessary for two reasons. Alcoho...  Read Full »

What should I do to prevent my recurring GERD symptoms?

Query: Hello doctor, I was diagnosed with eosinophilic esophagitis, GERD, and hiatal hernia three years back through an endoscopy. My symptoms during the period were non-cardiac chest pain (all cardiac tests were negative), infrequent regurgitation, and muscle tightness in my abdomen and shoulders. The do...  Read Full »


Dr. Ajeet Kumar

Answer: Hello, Welcome to icliniq.com. Well, the biopsy report (attachment removed to protect patient identity) does not show eosinophilic esophagitis, nor it showed that you have Barrett's esophagus. You have a sliding hernia and had significant reflux related esophagitis. I feel that this is again the r...  Read Full »

I underwent GERD surgery. Should I have to take PPI life-long?

Query: Hi doctor, I am concerned about my husband's health. He is taking PPI medication for ten years now called Omeprazole. We think he has to quit the medication. Could you please recommend to us what to do? How to start? I am also extremely worried about his liver. I know about the damage PPI may cause...  Read Full »


Dr. Ajeet Kumar

Answer: Hello, Welcome to icliniq.com. Well, there are very few indications of lifelong PPI (proton pump inhibitors). 1. Patient has GERD with Barrett's esophagus and premalignant findings such as dysplasia 2. Post fundoplication (GERD surgery) if the patient on follow-up has Barrett's esophagus or evid...  Read Full »

Can PPI cause stomach pain?

Query: Hello doctor, I have multiple problems with my stomach, it all began two years ago after taking pills which I was allergic to. My stomach became inflamed with a lot of acids, chronic antrum gastritis, and acid reflux. My stool was too soft, and I did not take any pill because my doctor did not give...  Read Full »


Dr. Babu Lal Meena

Answer: Hi, Welcome to icliniq.com. All the problems can be explained by dyspepsia. Although there are certain issues like normal endoscopy and absence of inflammation. And on endoscopy reports (attachment removed to protect patient identity), there is no obvious granulation tissue seen. There may be som...  Read Full »

Kindly suggest a permanent remedy for my long-term acid reflux problem.

Query: Hi doctor, I have suffered from reflux for over 10 years now, but usually quite manageable. It waxes and wanes. There are periods where I can have no symptoms, eat trigger foods without problems, and take Gaviscon now and then, and there are periods where I have to take 40 mg of PPI daily to keep ...  Read Full »


Dr. Ajeet Kumar

Answer: Hello, Welcome to icliniq.com. I have read your history and seen the report of gastric scintigraphy (attachment removed to protect patient identity). You do not have gastroparesis, a fraction of 25% at 2 hours post-meal within the stomach is a normal finding. Ideally, it should have been done for...  Read Full »

What tablets can be taken for GERD?

Query: Hello doctor, I am a nurse. I had throat burning sensation, nausea, chest pain, feeling of a full stomach, nausea, and reflux symptoms one month ago and the doctor advised me for lifestyle modifications. I stopped coffee, I am sleeping for two hours after dinner and I am eating non-spicy food. I was...  Read Full »


Dr. Sumit Srivastava

Answer: Hello, Welcome to icliniq.com. It seems you have GERD (Gastroesophageal reflux disease), GERD which is the cause of your symptoms. GERD occurs when stomach acid or the stomach content flows back into your food pipe. The backwash irritates the lining of your esophagus and causes heartburn, chest...  Read Full »

Does a burning sensation in the epigastric region suggest Zollinger disease?

Query: Hello doctor, I am suffering from a burning sensation in the epigastric region since two months. It is gradually increasing. I took a PPI for 10 days. Then four days after stopping PPI, I tested for serum gastrin level and it was 110. Do I have Zollinger disease?  Read Full »


Dr. Noushif. M

Answer: Hello, Welcome to icliniq.com. Serum gastrin level should be checked and interpreted with caution as it needs overnight fasting, early morning testing and abstinence from acid-suppression medications, etc. It can go as high as up to 300 or 400 pg/mL with normal being up to 100 pg/mL in people wh...  Read Full »

Are bloating sensation, indigestion, and frequent use of toilet linked to prolonged PPI use?

Query: Hello doctor, I have taken tablets of Pantoprazole 20 mg for the last ten years to control GERD. Now, I am suffering from a frequent toilet, bloating sensation, gas, indigestion, and headaches. In addition, there seems to be a low level of stomach acid, creating issues due to the prolonged use of PP...  Read Full »


Dr. Penchilaprasad Kandikattu

Answer: Hi, Welcome to icliniq.com. Dear, about your health condition, chronic intake of proton pump inhibitors (PPIs) leads to decreased acid in the stomach, leading to subacute intestinal bacterial overgrowth (SIBO). This may lead to bloating and indigestion. So avoid processed sugars and bakery products...  Read Full »

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