Common "Hemolytic Disease" queries answered by top doctors | iCliniq

Hemolytic Disease

A hemolytic disease is a disorder where there is rapid destruction of red blood cells. The most common causes are sickle cell anemia and thalassemia. These conditions produce red blood cells that do not live for a longer period. The symptoms are abnormal paleness of skin, fever, weakness, dark-colored urine, and unable to do physical activity. Taking corticosteroid medicines and blood transfusions helps a lot.

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Why are all my reports normal except bilirubin levels?

Query: Hello doctor,Can you go through the test reports and suggest why the bilirubin is high?  Read Full »

Dr. Geetha Priyadarsini Kamminana

Answer: Hello, Welcome to I have been through the reports posted (attachment removed to protect patient identity), and it says there is a mild rise in the total bilirubin, predominantly indirect bilirubin. If the patient is asymptomatic, not to worry. Is there a history of icterus or jaundice ...  Read Full »

I have minor beta thalassemia. Why do I look pale?

Query: Hi doctor, I am a 22-year-old female and I have a minor beta thalassemia (heterozygous) which is supposed to be asymptomatic but I am very pale. This makes me extremely insecure especially when people keep pointing it out. Every day I get at least two people asking me what is wrong with me and why d...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to In thalassemia minor patient, Hb (hemoglobin) usually remains around 10 to 11 gm/dl. It is hemolytic anemia and so extramedullary erythropoiesis occurs in the bone marrow (attachment removed to protect patient identity). So, the mandible is also affected and become p...  Read Full »

My son has microcytic hypochromic anemia. Kindly help.

Query: Hello doctor,My son has microcytic hypochromic anemia and mild anisopoikilocytosis with ovalocytes seen. No hemoparasites seen. What can I do? Currently, he is taking Cyclosporin 100 mg, and previously, he used to take Prednisone 30 mg.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I have seen your attached reports (attachment removed to protect patient identity). As per the reports he is having autoimmune hemolytic anemia because of reticulocyte count high, normoblast is seen, DCT (direct Coombs test) positive, ICT (indirect Coombs test) posit...  Read Full »

My fiance's blood group and mine are different. Please help.

Query: Hi doctor, My blood group is AB+, and my fiance's blood group is AB-. Will different blood groups create problems in future, regarding baby's health or other issues?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to You and your fiance can marry without any problem. Do not worry about that. The only thing that has to be done is to check the baby's blood group. As your blood group is Rh negative, so if the baby's blood group is Rh positive then it might lead to Rh incompatibility, ...  Read Full »

What is the possibility of a baby acquiring thalassemia?

Query: Hi doctor, My wife and I are both 29 years old. I have been diagnosed with hemoglobin E disease. My hemoglobin A is 68.7 g/dL, hemoglobin F is 9 g/dL, and hemoglobin E and A2 are 26 g/dL. And my wife has been diagnosed with a hemoglobin E trait. Her hemoglobin A is 9.1 g/dL and hemoglobin E and A2 a...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to I have gone through your attached reports (attachment removed to protect patient identity) and history. 1. Hemoglobin E disease or trait is an autosomal recessive condition. You are hemoglobin E disease patient, which means you are homozygous, and your wife has hemoglob...  Read Full »

My son is G6PD deficient and has anemia. Please help.

Query: Hi doctor, My son is G6PD deficient. He is already 10 months old. We have been having CBC since the first month and the result is somehow close. In his latest result, just taken yesterday, RBC is 4.09 (unit:x10^6/μL), hemoglobin is 112 (g/L), hematocrit is 0.33 (L/L) and WBC is 12000 x10^9/μL). Di...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to Do not try or stop medication on your own. It is advisable to visit his pediatrician or hematologist for an examination. Your child's hemoglobin level remains persistently low as per history. So, chronic hemolysis or intermittent hemolysis might be there. Clinical s...  Read Full »

I and my fiance have same blood group. Will it affect our baby?

Query: Hi doctor, I am 30 years old. I am planning to get married to a girl who is known to me. We have a very good understanding. But, we have the same blood group that is O-positive. Since the blood group is a factor in having babies, do you think having the same positive blood group could create proble...  Read Full »

Dr. Prakash. H. M.

Answer: Hi, Welcome to I read your query and understand your concern. There are two major blood group systems and more than 400 minor blood group systems. The major blood group systems are the ABO system and the Rhesus system, which are important. In the ABO system, there is A, B, AB, and O....  Read Full »

Why did my hemoglobin keep dropping all the time?

Query: Hello doctor,Please can you interpret my recent laboratory report? Why my hemoglobin is kept dropping all the time? Why my blood report is abnormal? Do you think I have blood cancer? Or any other cancer? Do you want me to go to an oncologist?  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello,Welcome to, I am giving you my opinion regarding your reports (attachment removed to protect patient identity). Your CBC showing microcytic hypochromic anemia. Anemia means a low hemoglobin level oxygen-carrying capacity of blood gets affected. Your reticulocyte is high and ...  Read Full »

How to manage hereditary spherocytosis?

Query: Hello doctor,I have been diagnosed with mild hereditary spherocytosis. My eyes are still yellow. Is it unlikely hematologist who diagnosed me three years ago was misdiagnosed? I do not doubt he knows his stuff. More about me getting worried. I lost weight a couple of months ago. I went very yellow i...  Read Full »

Dr. Singh Smrita

Answer: Hello, Welcome to I have gone through your laboratory reports (attachment removed to protect patient identity) and they are consistent with the diagnosis made by your doctor. The yellowish tint of the eyes is due to increased bilirubin levels. This is due to the increased red blood ...  Read Full »

How cam someone get rid of anemia?

Query: Hello doctor, How can someone get rid of anemia? It is not getting cured for the last four years. Now it has gone to serious condition in spite of many treatments.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to The treatment of anemia depends upon the underlying cause of anemia. If it is the case of iron deficiency anemia, then get treated with iron tablets, iron sucrose injection or blood transfusion according to severity. In the case of megaloblastic anemia, Vitamin B1...  Read Full »

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