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Can Filgrastim injections cause TLC levels to rise?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am in the eighth week of an IVF pregnancy. I have already had three miscarriages before. I am on Filgrastim injections (10 units of insulin syringe), Dexona, Duphaston, Estrabet 2 mg two tablets thrice a day. My doctor got some blood tests done yesterday. The TLC was at 21000 per microliter of blood. So, the doctor told me to get this repeated today. Today my TLC count was 21000 per microliter of blood. Could you please tell me if this increased level is fatal for my baby? Should I be worried?

Answered by Dr. Singh Smrita

Education:

MBBS

Professional Bio:

Dr. Singh Smrita is a General Practitioner and a Family Physician specializing in Pathology and Hematology. She has expertise in diagnosing and managing blood disorders, anemia, infections, and immune-related conditions. She is skilled in laboratory diagnostics, interpretation of blood tests, and personalized treatment plans. Dr. Singh also focuses on preventive care, patient education, and holistic management of chronic diseases.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

The Filgrastim injection that you are taking is responsible for the elevated TLC (total lymphocyte count). But you need not worry as the function of the Filgrastim is to cause multiplication of the white blood cells. Studies have shown that Filgrastim after IVF (in vitro fertilization) improves the implantation rate of the embryo. So, in your case, it is helping your pregnancy and preventing miscarriage. It is not going to harm your baby. So, you can relax and follow your doctor's instructions.

Regards.

Medically reviewed by iCliniq medical review team
Published At November 7, 2017
Reviewed At March 5, 2025

Education:

MBBS

Professional Bio:

Dr. Singh Smrita is a General Practitioner and a Family Physician specializing in Pathology and Hematology. She has expertise in diagnosing and managing blood disorders, anemia, infections, and immune-related conditions. She is skilled in laboratory diagnostics, interpretation of blood tests, and personalized treatment plans. Dr. Singh also focuses on preventive care, patient education, and holistic management of chronic diseases.

This doctor is not available for online consultations on the platform anymore.

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Education:

MBBS

Professional Bio:

Dr. Singh Smrita is a General Practitioner and a Family Physician specializing in Pathology and Hematology. She has expertise in diagnosing and managing blood disorders, anemia, infections, and immune-related conditions. She is skilled in laboratory diagnostics, interpretation of blood tests, and personalized treatment plans. Dr. Singh also focuses on preventive care, patient education, and holistic management of chronic diseases.

This doctor is not available for online consultations on the platform anymore.

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