HomeAnswersHematologyhigh lymphocyte countPlease interpret my friend's blood report for increased lymphocytes.

What if lymphocytes are higher than normal?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Kamal Kant Sahu

Medically reviewed by

Dr. Vinodhini J.

Published At April 27, 2020
Reviewed AtJuly 27, 2023

Patient's Query

Hi doctor,

I am curious about my friend's blood results. Blood tests show that his lymphocytes abs is 5.71 before six months, and 5.35 before three months. (Compared to the normal range that came with the results which is 1.30 to 3.60 x 10^9/L). Do you think is there something to be worried about?

Hello,

Welcome to icliniq.com.

I reviewed the records. (attachment removed to protect patient identity).

Having more lymphocyte count is known as lymphocytosis.

1. Benign or reactive lymphocytosis: Transient nature can be seen in an infectious disease like viral illness. This does not seem to be the case as it persists for a few months. Other causes, that could persist are noninfectious causes like stress, drug reaction, having spleen removed in the past, etc.

2. Malignant lymphocytosis: There is an entity called chronic lymphoproliferative disorders (CLPD), this is a very slow-growing blood malignancy, usually happens in individuals more than 60 to 65 years. Some times patients do throw symptoms like low-grade fever, weight loss, anemia, night sweats, etc. They may or may not be associated with low platelet count to anemia which is not the case with your friend.

With all this background knowledge, please see which ones is fitting for him. I will discuss the worse scenario because I guess you will be curious otherwise. Having CLPD is less likely as your friend is young, and he is not having anemia or low platelet counts.

Regarding the CLPD prognosis, it is one of the very slow-growing entity. We do not treat the early stages, as well as they, are so slow, treating has more drug side effects than the CLPD itself.

Getting a flowcytometry is rational in his case. But it is not urgent, you can wait for even few months if there is an issue of lockdown due to Coronavirus. Again, I am not saying he has any particular disease, but I want to explain everything in detail so that you have a good understanding.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Kamal Kant Sahu

Dr. Kamal Kant Sahu

Hematology

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