Histopathological Examination

Histopathological examination is viewing tissues and other cells obtained through biopsy under a microscope. Histological sections are made of the biopsy specimen, which are then mounted on a glass slab to view under the microscope. It is used to diagnose the type of cancer cells present and the manifestation of the disease.

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The tags on my penis are flexible without pain. Does it indicate skin tags or genital warts?

Query: Hi doctor, I was sexually assaulted last year. I got tested for all STDs, and everything came back negative. I also have type 1 diabetes with skin issues. I have some skin tags on my penis, and I showed my condition to a clinic, and the doctor told me that it is just skin tags. These tags are painl...  Read Full »


Dr. Bharatesh Devendra Basti

Answer: Hi, Welcome to icliniq.com. Thank you for the query. I have gone through the photos and details (attachment removed to protect patient identity). If they are movable and flexible, the lesion may be due to skin tags, as mentioned in case details. But warts also have to be ruled out. The differe...  Read Full »

Can we get a definitive diagnosis by a histopathological examination?

Query: Hi doctor, I have a few doubts regarding the pathology reports. Please clarify. It seems like advances in pathology is increasing diagnostic confidence. Can alcoholic liver disease biopsy result ever be 100% accurate by itself? Labeling something as "consistent with" could be a real problem for all ...  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. Histopathology examination by biopsy is the most confirmatory method for many pathological conditions. Hyperlipidemia can lead fatty liver condition, which can be because of alcohol as well. From histopathology examination, it can be surely said that whether it is an in...  Read Full »

My testicular ultrasound shows multiple solid nodules. Is biopsy needed?

Query: Hi doctor, I have had an ultrasound on my testicles and found multiple solid nodules or lumps and lesions in both testicles. He strongly suspects germ cell tumors. I have had blood tests done, and tumor markers and everything else is normal. I will be seeing a urologist in about two weeks. Do I have...  Read Full »


Dr. Arvind Guru

Answer: Hi,Welcome to icliniq.com.Any testicular mass is treated as cancer unless proven otherwise. That is why it is advised to evaluate the lesions found by patient or ultrasound by surgical removal and detailed pathological examination.Whereas for most other sites, the biopsy is possible. The biopsy is n...  Read Full »

Does my mum require surgery for her benign brain tumor?

Query: Hi doctor, My mom was admitted to the hospital due to an extreme headache, clicking sound in the head and high blood pressure. CAT scan revealed that she had a benign brain tumor and no surgery will probably be needed. After making an MRI, another neurosurgeon said she would have to remove it as it...  Read Full »


Dr. Hitesh Kumar

Answer: Hello, Welcome to icliniq.com. The lesion in the MRI brain of your mom is a small one on the left side. It is very adjacent to dura mater and showing contrast enhancement. This size of the lesion is very less likely to produce a headache by pressure effect. But, it is very important to find the exac...  Read Full »

I scratched a mole with my nails. Do I need to be worried?

Query: Hi doctor, I scratched a mole with my nail. It is a tiny scratch, and I do not even know if it is a mole. It appeared a few years ago. Now, I am worried. I have also attached the photo of it. Can you please advise me if it is dangerous?  Read Full »


Dr. Gaurang Gupta

Answer: Hello, Welcome to icliniq.com. You should not have scratched the mole as scratching increase the chance of malignancy in otherwise benign mole. Presently, what I can see is the erosion (attachment removed to protect patient identity), so at this stage, even dermoscopy would not be able to find out...  Read Full »

What happens if the breast specimen sent for histopathological examination is delayed by three hours?

Query: Hello doctor, If a breast specimen is sent to the laboratory for routine histopathology and the breast panel was delayed by three hours, will there be a problem in running the tests? Will the breast panel not be processed because of the delay?  Read Full »


Dr. Utkarsh Sharma

Answer: Hello, Welcome to icliniq.com. I understand your concern and will definitely help you out. A breast specimen should be kept in formalin fixative within one hour of resection for optimal immunohistochemistry (breast panel) results. The most recent guidelines for ER (estrogen receptor), PR (proges...  Read Full »

I have a lesion that changes color frequently. What to do?

Query: Hi doctor, I have attached a photo for your reference. Is this sign dangerous? It started almost 20 years ago to become dark and it became to be lighter around 5 years ago. Two days ago, again I have noticed this transformation with a white surface and that is healing now. It is around 4 mm. Please ...  Read Full »


Dr. Atishay Bukharia

Answer: Hi, Welcome back to icliniq.com. Is there any complaint in it? How many such lesions are there? Revert back with the answers to the above questions to a dermatologist online --> https://www.icliniq.com/ask-a-doctor-online/dermatologist  Read Full »

Can a single genital wart exist unchanged for over 10 years?

Query: Hello doctor, I am not sure why I never bothered to ask these questions before now, but I suppose it is better late than never. I have what appears to be a single genital wart just below the head. I have had it since I was 16 years old. I went through five years in the military with this without an...  Read Full »


Dr. Sampada Avinash Thakare

Answer: Hello, Welcome to icliniq.com. A single wart cannot exist for such a long time. There has to be an increase in the number. Are you sure it is a genital wart? Were you diagnosed by a dermatologist? Clinical photographs would have helped. For more information consult a dermatologist online ...  Read Full »

Please give your opinion on the moles on my back.

Query: Hi doctor, I have some moles on my back and that in my opinion look suspicious. What do you think? Please clarify.  Read Full »


Dr. Atishay Bukharia

Answer: Hi, Welcome to icliniq.com. Please send the photographs to get a better opinion. Thank you. Revert back with the photos to a dermatologist online --> https://www.icliniq.com/ask-a-doctor-online/dermatologist  Read Full »

How can a 4 cm dermoid ovarian cyst be treated?

Query: Hi doctor, I am a 34 year old female, and I had my right ovary and tube removed during C-section, due to a 4.5 cm dermoid cyst. The cyst was found during an ultrasound scan, five years back. The surgeon said a cystectomy was no possible because the cyst had completely replaced the ovary. Could you p...  Read Full »


Dr. Parth R Goswami

Answer: Hi, Welcome to icliniq.com. I have gone through your attached reports (attachment removed to protect patient identity). Let me tell you, your right-sided cyst was having benign germ cell tumor that is a dermoid cyst, which is called as a mature cystic teratoma. Such a cyst is filled with cheesy mate...  Read Full »

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