Histopathological Examination

Histopathological examination is viewing tissues and other cells obtained through biopsy under a microscope. Histological sections are made of the biopsy specimen, which are then mounted on a glass slab to view under the microscope. It is used to diagnose the type of cancer cells present and the manifestation of the disease.

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All the answers published in this website are written by Verified medical doctors, therapists and health experts. The Content has been moderated by iCliniq medical review team before publication. Post your medical clarifications on iCliniq by choosing the right specialty and get them answered. Your medical queries will be answered 24/7 by top doctors from iCliniq.

I scratched a mole with my nails. Do I need to be worried?

Query: Hi doctor, I scratched a mole with my nail. It is a tiny scratch, and I do not even know if it is a mole. It appeared a few years ago. Now, I am worried. I have also attached the photo of it. Can you please advise me if it is dangerous?  Read Full »


Dr. Gaurang Gupta

Cosmetologist, Dermatologist, Hair Transplant Surgeon, Venereologist

Answer: Hello, Welcome to icliniq.com. You should not have scratched the mole as scratching increase the chance of malignancy in otherwise benign mole. Presently, what I can see is the erosion (attachment removed to protect patient identity), so at this stage, even dermoscopy would not be able to find out...  Read Full »

What happens if the breast specimen sent for histopathological examination is delayed by three hours?

Query: Hello doctor, If a breast specimen is sent to the laboratory for routine histopathology and the breast panel was delayed by three hours, will there be a problem in running the tests? Will the breast panel not be processed because of the delay?  Read Full »


Dr. Utkarsh Sharma

Pathologist, General Practitioner, Family Physician

Answer: Hello, Welcome to icliniq.com. I understand your concern and will definitely help you out. A breast specimen should be kept in formalin fixative within one hour of resection for optimal immunohistochemistry (breast panel) results. The most recent guidelines for ER (estrogen receptor), PR (proges...  Read Full »

I have a lesion that changes color frequently. What to do?

Query: Hi doctor, I have attached a photo for your reference. Is this sign dangerous? It started almost 20 years ago to become dark and it became to be lighter around 5 years ago. Two days ago, again I have noticed this transformation with a white surface and that is healing now. It is around 4 mm. Please ...  Read Full »


Dr. Atishay Bukharia

Cosmetologist, Dermatologist, Family Physician, General Practitioner, HIV AIDS Specialist, Venereologist

Answer: Hi, Welcome back to icliniq.com. Is there any complaint in it? How many such lesions are there? Revert back with the answers to the above questions to a dermatologist online --> https://www.icliniq.com/ask-a-doctor-online/dermatologist  Read Full »

Can a single genital wart exist unchanged for over 10 years?

Query: Hello doctor, I am not sure why I never bothered to ask these questions before now, but I suppose it is better late than never. I have what appears to be a single genital wart just below the head. I have had it since I was 16 years old. I went through five years in the military with this without an...  Read Full »


Dr. Sampada Avinash Thakare

Cosmetologist, Dermatologist, Venereologist

Answer: Hello, Welcome to icliniq.com. A single wart cannot exist for such a long time. There has to be an increase in the number. Are you sure it is a genital wart? Were you diagnosed by a dermatologist? Clinical photographs would have helped. For more information consult a dermatologist online ...  Read Full »

Please give your opinion on the moles on my back.

Query: Hi doctor, I have some moles on my back and that in my opinion look suspicious. What do you think? Please clarify.  Read Full »


Dr. Atishay Bukharia

Cosmetologist, Dermatologist, Family Physician, General Practitioner, HIV AIDS Specialist, Venereologist

Answer: Hi, Welcome to icliniq.com. Please send the photographs to get a better opinion. Thank you. Revert back with the photos to a dermatologist online --> https://www.icliniq.com/ask-a-doctor-online/dermatologist  Read Full »

How can a 4 cm dermoid ovarian cyst be treated?

Query: Hi doctor, I am a 34 year old female, and I had my right ovary and tube removed during C-section, due to a 4.5 cm dermoid cyst. The cyst was found during an ultrasound scan, five years back. The surgeon said a cystectomy was no possible because the cyst had completely replaced the ovary. Could you p...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. I have gone through your attached reports (attachment removed to protect patient identity). Let me tell you, your right-sided cyst was having benign germ cell tumor that is a dermoid cyst, which is called as a mature cystic teratoma. Such a cyst is filled with cheesy mate...  Read Full »

What is your opinion regarding my wife's colon polyp?

Query: Hi doctor, My wife has been detected to have a 1.5 cm sessile polyp in descending colon in colonoscopy. One doctor said that there is nothing to be worried as it is harmless and the other says just opposite. Please give your opinion.  Read Full »


Dr. Sadaf Mustafa

General Medicine Physician, Internal Medicine Physician

Answer: Hello, Welcome to icliniq.com. Before I answer your question, can you please kindly share some more information. Is this the only polyp detected? Does she have a family history of colon cancer? Did she have any bleeding or it was a screening colonoscopy? Is this her first colonoscopy? If no, then w...  Read Full »

Please give your suggestion for my mole.

Query: Hi doctor,I have a mole that has grown a lot and has changed its shape and color. It has also developed a lot of different shaped blood vessels inside it. I have taken a few good images showing the mole close and the various blood vessels, which are running though it. I am now pretty worried after...  Read Full »


Dr. Atishay Bukharia

Cosmetologist, Dermatologist, Family Physician, General Practitioner, HIV AIDS Specialist, Venereologist

Answer: Hi, Welcome to icliniq.com. Yes, you need to consult a dermatologist as the features are suggestive of malignancy. The final diagnosis could only be made on histopathological examination, which is considered as a gold standard. Many times, benign lesion also has the appearance of malignancy. But, if...  Read Full »

Is amelanotic melanoma a lesion to be concerned?

Query: Hello doctor, Does this lesion in my lower back (pink) appear to be worrisome for amelanotic melanoma? It now appears flesh-colored. Pictures attached.  Read Full »


Dr. Atishay Bukharia

Cosmetologist, Dermatologist, Family Physician, General Practitioner, HIV AIDS Specialist, Venereologist

Answer: Hi, Welcome to icliniq.com. I have seen the pictures. (attachment removed to protect patient identity). Yes, they are looking like melanoma. Signs of vascularization in the previous nevus is suggestive of melanoma. Kindly consult a local dermatologist as dermoscopic and histological examination...  Read Full »

What is the treatment for pancreatic rest?

Query: Hi doctor, Please find the attachment of the endoscopy report of my wife. She had stomach pain a long time ago, and we did the endoscopy. But, the doctor did not explain the reason to us. Could you please explain to me? What is pancreatic rest? What do you think about the nature of her polyps and th...  Read Full »


Dr. Ajit Naniksingh Kukreja

General Surgeon, Medical Gastroenterologist, Medical Oncologist, Paediatric Surgeon, Surgical Gastroenterologist, Surgical Oncologist

Answer: Hi, Welcome to icliniq.com. I have seen the endoscopy reports of your wife (attachment removed to protect patient identity). She has gastroesophageal reflux (heartburn). A pancreatic rest is a sort of ectopic pancreatic tissue in the gastroduodenal mucosa. It is always better to wait for a biopsy ...  Read Full »

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