Q. I am 4 months pregnant with hyperthyroidism. Is PTU good for me during pregnancy?

Answered by
Dr. Zulfiqar Ahmed
and medically reviewed by Dr. Vinodhini. J
This is a premium question & answer published on Apr 25, 2020 and last reviewed on: May 08, 2020

Hello doctor,

I am 26 years old. I have a problem with hyperthyroidism during my pregnancy. I am in my fourth month of pregnancy with TSH- 0.07, T4- 161, T3- 2.34. What are the complications with this? Is it good for me to take PTU.

Dr. Zulfiqar Ahmed

Diabetology Endocrinology
#

Hi,

Welcome to icliniq.com.

Hyperthyroidism in pregnancy is usually treated with Propylthiouracil 50-100 mg/day. Generally, treatment is withdrawn four weeks prior to delivery after which normal doses may be resumed. Your hormone levels are still very high, you need to increase your dose.

Pregnancies complicated by uncontrolled hyperthyroidism may result in higher incidences of spontaneous abortion (miscarriage), preterm labor, low birth-weight babies, or stillbirths. Complications of pregnancy, including pre-eclampsia (a condition associated with hypertension, low blood platelet count, protein in the urine, and mental changes) may also occur. So please increase your dosage.

Another thing I want to highlight is that you should do TSH (thyroid-stimulating hormone) receptor antibodies and to see what is the cause of your hyperthyroidism. Is it Graves’ disease. These antibodies can enter from the mother's blood to the baby's blood and stimulate the baby's thyroid gland. These antibodies should be measured in the mother during her second trimester of pregnancy because the values that are greater than five times normal have been associated with hyperthyroidism in the baby at birth.


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