What is the cause for worsening muscle and joint pain for a longer period?

Q. Experiencing muscle and joint pain for 10 years and is getting worse. What to do?

Answered by
Dr. Goswami Parth Rajendragiri
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Nov 23, 2019 and last reviewed on: Feb 28, 2023

Hello doctor,

I am experiencing muscle pain and joint pain for ten years which consistently got worse. The recent diagnosis shows leukocytosis. My WBC is consistently high at around 13000 to 15000. I also suffer fibromyalgia, migraines, TIA, unknown source of seizures, peripheral neuropathy, left hemiparesis, muscle disorder, muscle spasm-paresthesia, diabetic type 2, AVN of hips, DDJ and DDD disease.

I am currently taking Bacoflen 20 mg four times a day, Cymbalta 30 mg once daily, Valium 5 mg, Gabapentin 300 mg four times a day, Humalog, Metformin 1000 two times a day, Bydureon Pen once a week, and Medical Cannabis. I consulted a rheumatologist and a neurologist. Rheumatologist swore it was Lupus. The neurologist swore it was SPS.

My recent laboratory report:

1. Complement component C3C - 188H Range 90-180 (twice tested).

2. Glucose 168 mg/dL.

3. Alpha 1 globulin 4H - Range 0.2 - 0.3.

4. Gamma globulin 7L - Range 0.8 - 1.7.

5. Vitamin D - 18L - Range 30 - 100.

6. C-reactive protein 0.83H.



Welcome to icliniq.com. Your main presentation is chronic muscle pain and joint pain. For that specific cause rule out first like connective tissue disorder, muscle dystrophy, neuropathic pain, spinal problem, HIV, thyroid issue, etc.

For connective tissue panel testing, CT scan, serum TSH (thyroid-stimulating hormone) estimation, serum T4 estimation like investigations are useful. Here neurologist may perform investigation like NCV (nerve conduction velocity), EMG (electromyography), for finding the specific cause. According to the cause further specific treatment will be given. If SLE (systemic lupus erythematosus) suspected by rheumatologist then it will be confirmed by connective tissue panel testing that includes testing of anti-dsDNA, anti-Sm, etc. You are prescribed Gabapentine, muscle relaxant and Duloxetine drugs and these drugs can cause fibromyalgia or chronic fatigue syndrome. Control your diabetes as it can lead to neuropathic pain and other complications. As per report vitamin D looks out of range that is low, so for that Cholecalciferol sachet can be taken with milk once a week.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
I have dull, persistent aches and pain in abdomen. Is it due to dance practice?

.. your complaints, it seems you may be suffering from muscular pain if your pain is not related to any signs like change in bowel habits or related to any abnormality in periods or menstruation or any kind of change in stool or urine and any other associ   Read full

I am getting pain under ribs and in the back like muscle pull. What to do?

.. is suggestive of muscular pain. But it should also to rule out any cardiac cause. I will give you some medication, if you did not find any improvement, you consult a cardiologist for a complete cardiac profile, or I will provide you with some tests tha   Read full

I am being tested for antiphospholipid syndrome. What will the treatment be?

.. erythematosus (SLE) is an autoimmune condition. The condition can affect a single organ or multiple organ systems. DVT (deep vein thrombosis) in SLE is multifactorial. The most common cause is the presence of antiphospholipid antibodies.   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

PCOS and Liver Problems
The hormonal imbalances in polycystic ovary syndrome could cause liver diseases. Read the article to know the relationship between these medical conditions.  Read more»
Inferior Alveolar Nerve Lateralization Technique
The inferior alveolar nerve lateralization technique is a surgical lateralization technique to reposition the nerve. Read the article to know more about this.  Read more»
COVID-19 and Ebola: Similarities and Differences
This article gives a comparison and broader overview of the outbreak of the two deadliest diseases that showed a greater incidence over the last two decades.  Read more»

Ask your health query to a doctor online?

Ask a Hematologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.